Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease (Q38970893)

7 June 2018

review article

1 reference

title

Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease (English)

1 reference

7 June 2018

0 references

Boris Decourt

1

1 reference

7 June 2018

Debomoy K Lahiri

series ordinal

2

1 reference

7 June 2018

Marwan N Sabbagh

series ordinal

3

1 reference

7 June 2018

publication date

1 January 2017

1 reference

7 June 2018

Current Alzheimer Research

published in

1 reference

7 June 2018

volume

14

1 reference

7 June 2018

page(s)

412-425

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7 June 2018

issue

4

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7 June 2018

Brain cytokines and disease

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17 June 2018

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17 June 2018

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Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity

17 June 2018

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Tau-based therapeutic approaches for Alzheimer's disease - a mini-review.

17 June 2018

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Strategies for the management of adverse events associated with mTOR inhibitors

17 June 2018

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Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview

17 June 2018

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Lessons from a BACE1 inhibitor trial: off-site but not off base.

17 June 2018

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Schizophrenia-like disorder associated with etanercept treatment

17 June 2018

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Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications.

17 June 2018

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Tumor necrosis factor receptor 2: its contribution to acute cellular rejection and clear cell renal carcinoma

17 June 2018

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Calcineurin inhibitors: 40 years later, can't live without ...

17 June 2018

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Modeling Alzheimer's disease in transgenic rats

17 June 2018

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Elevated CNS inflammation in patients with preclinical Alzheimer's disease.

17 June 2018

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Impact of minocycline on neurodegenerative diseases in rodents: a meta-analysis

17 June 2018

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Growth factors in synaptic function

17 June 2018

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The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

17 June 2018

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Demyelination and other neurological adverse events after anti-TNF therapy

17 June 2018

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17 June 2018

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Elevated Aβ42 in aged, non-demented individuals with cerebral atherosclerosis

17 June 2018

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Proinflammatory cytokines, aging, and age-related diseases

17 June 2018

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γ-Secretase inhibitors and modulators

17 June 2018

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Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies

17 June 2018

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The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia

17 June 2018

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17 June 2018

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Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease

17 June 2018

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Early intervention with a small molecule inhibitor for tumor necrosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer's disease

17 June 2018

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Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

17 June 2018

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Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology

17 June 2018

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Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology

17 June 2018

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17 June 2018

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Neuroinflammation and synaptic loss

17 June 2018

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17 June 2018

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17 June 2018

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Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

17 June 2018

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Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer's disease.

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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The roles of TNF in brain dysfunction and disease

17 June 2018

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A meta-analysis of cytokines in Alzheimer's disease

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17 June 2018

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17 June 2018

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The nuclear factor NF-kappaB pathway in inflammation

17 June 2018

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Why pleiotropic interventions are needed for Alzheimer's disease.

17 June 2018

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The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases

17 June 2018

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Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

17 June 2018

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Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

17 June 2018

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Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction

17 June 2018

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17 June 2018

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17 June 2018

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Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

17 June 2018

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Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging

17 June 2018

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17 June 2018

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The role of cytokines in sleep regulation

17 June 2018

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Evidence for a cytokine model of cognitive function

17 June 2018

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Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice

17 June 2018

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TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

17 June 2018

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17 June 2018

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Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway

17 June 2018

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Transmembrane TNF-alpha mediates "forward" and "reverse" signaling, inducing cell death or survival via the NF-kappaB pathway in Raji Burkitt lymphoma cells

17 June 2018

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Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1.

17 June 2018

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Protective effects of NSAIDs on the development of Alzheimer disease

17 June 2018

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17 June 2018

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Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

17 June 2018

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TNF-mediated inflammatory disease.

17 June 2018

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Divergent roles for tumor necrosis factor-alpha in the brain

17 June 2018

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Dose translation from animal to human studies revisited

17 June 2018

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TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets.

17 June 2018

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Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

17 June 2018

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Physiological roles of muscle-derived interleukin-6 in response to exercise

17 June 2018

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Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

17 June 2018

1 reference

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Role of myokines in exercise and metabolism

17 June 2018

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Increased production of inflammatory cytokines in mild cognitive impairment

17 June 2018

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17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

NF-kappaB functions in the nervous system: from development to disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

High interleukin-6 plasma levels are associated with low HDL-C levels in community-dwelling older adults: the InChianti study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

17 June 2018

Immunomodulatory drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

GCF2/LRRFIP1 represses tumor necrosis factor alpha expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Signaling via NF-kappaB in the nervous system

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Microglia-derived tumor necrosis factor-alpha exaggerates death of newborn hippocampal progenitor cells in vitro

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Allele-specific binding to the -308 single nucleotide polymorphism site in the tumour necrosis factor-alpha promoter.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Cerebral pattern of pro- and anti-inflammatory cytokines in dementias

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Entry of blood-borne cytokines into the central nervous system: effects on cognitive processes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

The mosaic of immunosuppressive drugs.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Tumor necrosis factor signaling.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Possible beneficial role of exercise in modulating low-grade inflammation in the elderly

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

TNF ligands and receptors--a matter of life and death

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Neurotoxicity of immunosuppressive drugs

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Cytokine pathways and joint inflammation in rheumatoid arthritis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

The TNF and TNF receptor superfamilies: integrating mammalian biology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Modulation of epithelial and endothelial paracellular permeability by leukocytes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Penetration of neurotrophins and cytokines across the blood-brain/blood-spinal cord barrier

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Cellular localization of tumor necrosis factor alpha following focal cerebral ischemia in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Passage of cytokines across the blood-brain barrier

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Neurologic complications of FK 506

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

The molecular pathology of Alzheimer's disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Inhibition of in vitro immunoglobulin production by rapamycin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Relationship of TNF to interleukins

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Central delivery of iodine-125-labeled cetuximab, etanercept and anakinra after perispinal injection in rats: possible implications for treating Alzheimer's disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Physical exercise in MCI elderly promotes reduction of pro-inflammatory cytokines and improvements on cognition and BDNF peripheral levels.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Physical exercise improves peripheral BDNF levels and cognitive functions in mild cognitive impairment elderly with different bdnf Val66Met genotypes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Peripheral administration of an anti-TNF-α receptor fusion protein counteracts the amyloid induced elevation of hippocampal TNF-α levels and memory deficits in mice.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Selective acetyl- and butyrylcholinesterase inhibitors reduce amyloid-β ex vivo activation of peripheral chemo-cytokines from Alzheimer's disease subjects: exploring the cholinergic anti-inflammatory pathway.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

A phase 3 trial of semagacestat for treatment of Alzheimer's disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Neurological events with tumour necrosis factor alpha inhibitors reported to the Food and Drug Administration Adverse Event Reporting System.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

GCF2/LRRFIP1 promotes colorectal cancer metastasis and liver invasion through integrin-dependent RhoA activation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

A review: inflammatory process in Alzheimer's disease, role of cytokines.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Anticholinergics boost the pathological process of neurodegeneration with increased inflammation in a tauopathy mouse model.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Tumor necrosis factor-α: investigation of gene polymorphism and regulation of TACE-TNF-α system in patients with acute myocardial infarction

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Restraining tumor necrosis factor-alpha by thalidomide prevents the amyloid beta-induced impairment of recognition memory in mice

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Elevation of tumor necrosis factor-alpha in cerebrospinal fluid of autistic children.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Dexamethasone inhibits TNF-alpha synthesis more effectively in Alzheimer's disease patients than in healthy individuals.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Role of cytokines in the gene expression of amyloid β–protein precursor: Identification of a 5'-UTR-Binding nuclear factor and its implications in Alzheimer's disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Association between the TNFalpha-308 A/G polymorphism and the onset-age of Alzheimer disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

TNFalpha transport across the blood-brain barrier is abolished in receptor knockout mice.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Differential cellular expression of tumor necrosis factor-alpha and Type I tumor necrosis factor receptor after transient global forebrain ischemia.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Prostaglandin E2 stimulates amyloid precursor protein gene expression: inhibition by immunosuppressants.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

A study of the morphology and distribution of amyloid beta protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5328927

Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains

21 August 2018

1 reference

12 December 2020

Cytokines and feeding

1 reference

12 December 2020

TNF-alpha G308A polymorphism and the susceptibility to Alzheimer's disease: an updated meta-analysis

1 reference

12 December 2020

Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10

1 reference

12 December 2020

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation

1 reference

12 December 2020

A placebo-controlled, multiple ascending dose study to evaluate the safety, pharmacokinetics and pharmacodynamics of avagacestat (BMS-708163) in healthy young and elderly subjects

1 reference

12 December 2020

Increased levels of NF-kappaB inhibitors (IkappaBalpha and IkappaBgamma) in the intestinal mucosa of Crohn's disease patients during infliximab treatment

1 reference

12 December 2020

TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus

1 reference

12 December 2020

TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs

1 reference

12 December 2020

Inflammatory processes in Alzheimer's disease

1 reference

12 December 2020

10.2174/1567205013666160930110551

Identifiers

DOI

1 reference

7 June 2018

PMCID

5328927

1 reference

7 June 2018

PubMed ID

27697064

1 reference

7 June 2018