Tumor necrosis factor signaling. (Q34185821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Tumor necrosis factor signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

2

Pfizenmaier K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

3

Scheurich P

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 January 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

1 November 2019

language of work or name

English

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

45-65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json

publication type of scholarly work

1 November 2019

review article

1 reference

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Human pro-tumor necrosis factor is a homotrimer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Emerging families of cytokines and receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Modularity in the TNF-receptor family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Anti-tumor necrosis factor therapies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Apoptosis signaling by death receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cytokine regulation of secondary lymphoid organ development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Characterization of tumor necrosis factor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor receptor p55-deficient mice respond to acute Yersinia enterocolitica infection with less apoptosis and more effective host resistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane‐bound TNF in experimental cerebral malaria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Exacerbation of Mycobacterium tuberculosis enteritis masquerading as Crohn's disease after treatment with a tumor necrosis factor-alpha inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Isolated limb perfusion for extremity soft-tissue sarcomas, in-transit metastases, and other unresectable tumors: credits, debits, and future perspectives

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Evidence for the involvement of endotheliai cell integrin αVβ3 in the disruption of the tumor vascuiature induced by TNF and IFN-γ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Signal transduction by tumor necrosis factor and its relatives

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The Rel/NF-kappa B family: friend and foe.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NEMO/IKK gamma-deficient mice model incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NAK is an IkappaB kinase-activating kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Role of receptor-interacting protein in tumor necrosis factor-alpha -dependent MEKK1 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Roles of phosphatidylinositol 3-kinase and Rac in the nuclear signaling by tumor necrosis factor-alpha in rat-2 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibitors of ADP-Ribosylation Impair Inducible Nitric Oxide Synthase Gene Transcription through Inhibition of NF Kappa B Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A20 inhibits NF-kappa B activation downstream of multiple Map3 kinases and interacts with the I kappa B signalosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of early-immediate genes by tumer necrosis factor alpha contribute to liver repair following chemical-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Signaling by the germinal center kinase family of protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Direct Activation of Mitogen-Activated Protein Kinase Kinase Kinase MEKK1 by the Ste20p Homologue GCK and the Adapter Protein TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Reactive oxygen species are downstream products of TRAF-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of Interleukin-1β-induced Interleukin-6 Gene Expression in Human Fibroblast-like Synoviocytes by p38 Mitogen-activated Protein Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Involvement of FAN in TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of ERK1/2 and cPLA(2) by the p55 TNF receptor occurs independently of FAN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A model of the microtubule-kinesin complex based on electron cryomicroscopy and X-ray crystallography

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

DENN, a novel human gene differentially expressed in normal and neoplastic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Phosphorylation of Raf by ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor Necrosis Factor-α Supports the Survival of Osteoclasts through the Activation of Akt and ERK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The pathogenesis of vasodilatory shock

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Molecular Ordering of the Initial Signaling Events of CD95

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of TRAF2 signaling by self-induced degradation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Baculoviruses and apoptosis: the good, the bad, and the ugly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB signals induce the expression of c-FLIP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IEX -1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Blocking Caspase-3-Mediated Proteolysis of IKKβ Suppresses TNF-α-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation of NF-kappaB by FADD, Casper, and caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Correlation between Sustained c-Jun N-terminal Protein Kinase Activation and Apoptosis Induced by Tumor Necrosis Factor-α in Rat Mesangial Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibition of the Expression of Mitogen-activated Protein Phosphatase-1 Potentiates Apoptosis Induced by Tumor Necrosis Factor-α in Rat Mesangial Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibition of JNK activation through NF-κB target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

JNK/SAPK activity contributes to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

A kinase-independent function of Ask1 in caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF-α activates at least two apoptotic signaling cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Four deaths and a funeral: from caspases to alternative mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Caspase-independent cell killing by Fas-associated protein with death domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Programmed cell death induced by ceramide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Functional analysis of acid and neutral sphingomyelinases in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Requirement of FADD for tumor necrosis factor-induced activation of acid sphingomyelinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TNF Receptor Death Domain-associated Proteins TRADD and FADD Signal Activation of Acid Sphingomyelinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cathepsin D targeted by acid sphingomyelinase-derived ceramide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The autophagosomal-lysosomal compartment in programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The p70 tumor necrosis factor receptor mediates cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

JunD protects cells from p53-dependent senescence and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

PARP is important for genomic stability but dispensable in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189

7 January 2021