DNA damage checkpoint recovery and cancer development (Q38405830)

2 September 2017

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title

DNA damage checkpoint recovery and cancer development (English)

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2 September 2017

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Haiyong Wang

1

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2 September 2017

Xiaoshan Zhang

series ordinal

2

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2 September 2017

Lisong Teng

series ordinal

3

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2 September 2017

Randy J Legerski

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

2 April 2015

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Experimental Cell Research

2 September 2017

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2 September 2017

334

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2 September 2017

2

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2 September 2017

350-358

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

2 September 2017

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DNA damage checkpoints: from initiation to recovery or adaptation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The ATR barrier to replication-born DNA damage.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Chk1 is essential for chemical carcinogen-induced mouse skin tumorigenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

DNA damage checkpoints in stem cells, ageing and cancer.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

DNA damage signalling guards against activated oncogenes and tumour progression

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

An oncogene-induced DNA damage model for cancer development

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

DNA damage checkpoint inactivation: adaptation and recovery

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Wip1-deficient mice are resistant to common cancer genes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Checkpoint adaptation and recovery: back with Polo after the break

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Human claspin is required for replication checkpoint control

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Cleavage and degradation of Claspin during apoptosis by caspases and the proteasome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Targeting polo-like kinase 1 for cancer therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The Greatwall kinase: a new pathway in the control of the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Greatwall and Polo-like kinase 1 coordinate to promote checkpoint recovery

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The overlooked greatwall: a new perspective on mitotic control

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and target of anticancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Turning off the G2 DNA damage checkpoint

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Deacetylase Rpd3 facilitates checkpoint adaptation by preventing Rad53 overactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Expression of polo-like kinase 1 (PLK1) protein predicts the survival of patients with gastric carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Polo‐like kinase 1 (PLK1) is overexpressed in primary colorectal cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Polo-like kinase: a novel marker of proliferation: correlation with estrogen-receptor expression in human breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The balance of Polo-like kinase 1 in tumorigenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Polo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Evaluation of claspin as a proliferation marker in human cancer and normal tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Oncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Over-expression of wild-type p53-induced phosphatase 1 confers poor prognosis of patients with gliomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Protein serine/threonine phosphatases as binding proteins for okadaic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

A new target for proteasome inhibitors: FoxM1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

Regulation of Rad17 protein turnover unveils an impact of Rad17-APC cascade in breast carcinogenesis and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.03.011

10.1016/J.YEXCR.2015.03.011

7 January 2021

Identifiers

DOI

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2 September 2017

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