Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication (Q29617915)

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22 December 2019

title

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication (English)

2 references

PubMed

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30 April 2017

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22 December 2019

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1

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22 December 2019

Marzia Fumagalli

2

1 reference

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22 December 2019

Patrizia Gasparini

5

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22 December 2019

Paolo Nuciforo

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22 December 2019

Roberta Maestro

11

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22 December 2019

Fabrizio Daddadifagagna

13

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22 December 2019

author name string

Angelo Cicalese

3

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22 December 2019

Sara Piccinin

4

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22 December 2019

Chiara Luise

6

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22 December 2019

Catherine Schurra

7

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22 December 2019

Massimiliano Garre'

8

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22 December 2019

Aaron Bensimon

10

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22 December 2019

Pier Giuseppe Pelicci

12

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publication date

1 November 2006

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22 December 2019

language of work or name

1 reference

30 April 2017

2 references

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30 April 2017

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22 December 2019

volume

444

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22 December 2019

issue

7119

2 references

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22 December 2019

page(s)

638-642

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

22 December 2019

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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Oncogene-induced senescence as an initial barrier in lymphoma development

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Tumour biology: senescence in premalignant tumours

21 January 2018

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Cell senescence and cancer

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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Cell-cycle checkpoints and cancer

21 January 2018

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

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Transformation of normal human cells in the absence of telomerase activation

21 January 2018

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A p53-dependent checkpoint pathway prevents rereplication

21 January 2018

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Loss of Geminin induces rereplication in the presence of functional p53

21 January 2018

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Single DNA molecule analysis: applications of molecular combing

21 January 2018

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Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells

21 January 2018

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p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation

21 January 2018

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ATR Regulates Fragile Site Stability

21 January 2018

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Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

21 January 2018

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A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

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Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 January 2018

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The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle

21 January 2018

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Improved cervical smear assessment using antibodies against proteins that regulate DNA replication

21 January 2018

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Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro

21 January 2018

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 January 2018

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Oncogenic activity of Cdc6 through repression of the INK4/ARF locus

21 January 2018

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Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

21 January 2018

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Lack of PTEN sequesters CHK1 and initiates genetic instability.

21 January 2018

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

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DNA damage-dependent nuclear dynamics of the Mre11 complex

21 January 2018

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

21 January 2018

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7 January 2021

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30 April 2017

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Dimensions Publication ID

22 December 2019

1007876716

0 references

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3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017