MicroRNA regulation by RNA-binding proteins and its implications for cancer (Q37913018)

25 August 2017

title

MicroRNA regulation by RNA-binding proteins and its implications for cancer (English)

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25 August 2017

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3

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25 August 2017

author name string

Marieke van Kouwenhove

series ordinal

1

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25 August 2017

Martijn Kedde

series ordinal

2

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25 August 2017

publication date

5 August 2011

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25 August 2017

language of work or name

English

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published in

Nature Reviews Cancer

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25 August 2017

volume

11

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25 August 2017

issue

9

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25 August 2017

page(s)

644-656

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publication type of scholarly work

25 August 2017

review article

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MicroRNAs: target recognition and regulatory functions

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Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

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The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis

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Mechanisms of the epithelial-mesenchymal transition by TGF-beta

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A splicing-independent function of SF2/ASF in microRNA processing

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The gene encoding the splicing factor SF2/ASF is a proto-oncogene

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Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

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Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing

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A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

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Lin28: A microRNA regulator with a macro role

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STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

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The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

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Posttranscriptional regulation of miRNAs harboring conserved terminal loops.

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The terminal loop region controls microRNA processing by Drosha and Dicer

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A microRNA in a multiple-turnover RNAi enzyme complex

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

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Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

31 March 2020

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Essential and overlapping functions for mammalian Argonautes in microRNA silencing

31 March 2020

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The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing

31 March 2020

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

31 March 2020

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A parsimonious model for gene regulation by miRNAs.

31 March 2020

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The impact of microRNAs on protein output

31 March 2020

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Mammalian microRNAs predominantly act to decrease target mRNA levels

31 March 2020

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Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

31 March 2020

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Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

31 March 2020

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Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo

31 March 2020

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P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression

31 March 2020

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Identification of novel argonaute-associated proteins

31 March 2020

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MicroRNA silencing through RISC recruitment of eIF6

31 March 2020

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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

31 March 2020

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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

31 March 2020

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Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

31 March 2020

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Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies

31 March 2020

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The Hsp90 inhibitor geldanamycin abrogates colocalization of eIF4E and eIF4E-transporter into stress granules and association of eIF4E with eIF4G.

31 March 2020

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Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes

31 March 2020

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A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

31 March 2020

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HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells

31 March 2020

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The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

31 March 2020

1 reference

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

31 March 2020

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Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

31 March 2020

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Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2

31 March 2020

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Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

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The enzymes and control of eukaryotic mRNA turnover

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The human homolog of yeast SEP1 is a novel candidate tumor suppressor gene in osteogenic sarcoma

31 March 2020

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Diverse molecular functions of Hu proteins

31 March 2020

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Relief of microRNA-mediated translational repression in human cells subjected to stress

31 March 2020

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HuR regulates p21 mRNA stabilization by UV light

31 March 2020

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ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

31 March 2020

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Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.

31 March 2020

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Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR.

31 March 2020

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HuR recruits let-7/RISC to repress c-Myc expression

31 March 2020

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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

31 March 2020

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MicroRNA-125a represses cell growth by targeting HuR in breast cancer

31 March 2020

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miR-519 suppresses tumor growth by reducing HuR levels

31 March 2020

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Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs

31 March 2020

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Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.

31 March 2020

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Dissecting eIF4E action in tumorigenesis

31 March 2020

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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

31 March 2020

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Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.

31 March 2020

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Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

31 March 2020

1 reference

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

31 March 2020

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A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics

31 March 2020

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Folding of A+U-rich RNA elements modulates AUF1 binding. Potential roles in regulation of mRNA turnover

31 March 2020

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Structural remodeling of an A + U-rich RNA element by cation or AUF1 binding

31 March 2020

1 reference

Regulation of human vascular endothelial growth factor mRNA stability in hypoxia by heterogeneous nuclear ribonucleoprotein L

31 March 2020

1 reference

Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L

31 March 2020

1 reference

A stress-responsive RNA switch regulates VEGFA expression.

31 March 2020

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A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR.

31 March 2020

1 reference

miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts

31 March 2020

1 reference

High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation

31 March 2020

1 reference

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

31 March 2020

1 reference

Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo

31 March 2020

1 reference

Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

31 March 2020

1 reference

Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

31 March 2020

1 reference

Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site

31 March 2020

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Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts

31 March 2020

1 reference

Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling

31 March 2020

1 reference

Stability of the LATS2 Tumor Suppressor Gene Is Regulated by Tristetraprolin

31 March 2020

1 reference

Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin

31 March 2020

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The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis

31 March 2020

1 reference

Decoding ARE-mediated decay: is microRNA part of the equation?

31 March 2020

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Involvement of microRNA in AU-rich element-mediated mRNA instability

31 March 2020

1 reference

CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling

31 March 2020

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Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

31 March 2020

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Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

31 March 2020

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CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation

31 March 2020

1 reference

MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein

31 March 2020

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Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma

31 March 2020

1 reference

Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system

31 March 2020

1 reference

A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility

31 March 2020

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Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets

31 March 2020

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A structural-based statistical approach suggests a cooperative activity of PUM1 and miR-410 in human 3'-untranslated regions

31 March 2020

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AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.

31 March 2020

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Switching from repression to activation: microRNAs can up-regulate translation

31 March 2020

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31 March 2020

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Biased alternative polyadenylation in human tissues

31 March 2020

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Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

31 March 2020

1 reference

Differential repression of alternative transcripts: a screen for miRNA targets

31 March 2020

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Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

31 March 2020

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RNA processing and its regulation: global insights into biological networks

31 March 2020

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Genome-wide measurement of RNA secondary structure in yeast

31 March 2020

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miRBase: microRNA sequences, targets and gene nomenclature

31 March 2020

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Approaches to microRNA discovery

31 March 2020

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A mammalian microRNA expression atlas based on small RNA library sequencing

31 March 2020

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The code within the code: microRNAs target coding regions

31 March 2020

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Small non-coding RNAs in animal development

31 March 2020

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The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

31 March 2020

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The diverse functions of microRNAs in animal development and disease

31 March 2020

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MicroRNA regulation of core apoptosis pathways in cancer.

31 March 2020

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MicroRNAs and cancer--new paradigms in molecular oncology

31 March 2020

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Role of microRNAs in vascular diseases, inflammation, and angiogenesis

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MicroRNAs as regulators of epithelial-mesenchymal transition.

31 March 2020

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MicroRNAs--the micro steering wheel of tumour metastases

31 March 2020

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MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

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Reprogramming of miRNA networks in cancer and leukemia

31 March 2020

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31 March 2020

miRNAs in human cancer

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MicroRNA signatures in human cancers

31 March 2020

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MicroRNAs and cancer: short RNAs go a long way.

31 March 2020

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Genetic variation in microRNA networks: the implications for cancer research

31 March 2020

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Biogenesis of small RNAs in animals

31 March 2020

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The widespread regulation of microRNA biogenesis, function and decay

31 March 2020

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RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

31 March 2020

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A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

31 March 2020

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The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

31 March 2020

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Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1)

31 March 2020

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DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish

31 March 2020

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Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins

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Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind

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Regulation of mRNA translation and stability by microRNAs

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Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu.

31 March 2020

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Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays

31 March 2020

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Target RNA motif and target mRNAs of the Quaking STAR protein

31 March 2020

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Genomic systematic evolution of ligands by exponential enrichment (Genomic SELEX) for the identification of protein-binding RNAs independent of their expression levels

31 March 2020

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HITS-CLIP yields genome-wide insights into brain alternative RNA processing

31 March 2020

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Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs

31 March 2020

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Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

31 March 2020

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A novel mRNA affinity purification technique for the identification of interacting proteins and transcripts in ribonucleoprotein complexes

31 March 2020

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MicroRNAs: Oncogenes, tumor suppressors or master regulators of cancer heterogeneity?

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21822212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Posttranscriptional regulation of cancer traits by HuR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21822212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRC3107

1 reference

25 August 2017

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