Biogenesis of small RNAs in animals (Q27861013)

Europe PubMed Central

title

Biogenesis of small RNAs in animals (English)

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Jinju Han

2

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ORCID Public Data File 2021

V. Narry Kim

series ordinal

1

object named as

V Narry Kim

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author name string

Mikiko C Siomi

series ordinal

3

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language of work or name

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February 2009

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published in

Nature Reviews Molecular Cell Biology

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volume

10

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page(s)

126-39

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issue

2

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cites work

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

31 March 2020

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

31 March 2020

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An extensive class of small RNAs in Caenorhabditis elegans

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Identification of novel genes coding for small expressed RNAs

31 March 2020

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Elucidation of the small RNA component of the transcriptome

31 March 2020

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Genome sequencing in microfabricated high-density picolitre reactors

31 March 2020

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Computational identification of Drosophila microRNA genes

31 March 2020

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Human microRNA prediction through a probabilistic co-learning model of sequence and structure

31 March 2020

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Bioinformatic discovery of microRNA precursors from human ESTs and introns

31 March 2020

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MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans

31 March 2020

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Small RNAs: regulators and guardians of the genome

31 March 2020

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

31 March 2020

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A distinct small RNA pathway silences selfish genetic elements in the germline

31 March 2020

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Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

31 March 2020

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Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

31 March 2020

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Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

31 March 2020

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The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

31 March 2020

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Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

31 March 2020

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An endogenous small interfering RNA pathway in Drosophila

31 March 2020

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MicroRNAS and their regulatory roles in plants

31 March 2020

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Functions of microRNAs and related small RNAs in plants

31 March 2020

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Plant microRNA: a small regulatory molecule with big impact

31 March 2020

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RNAi-directed assembly of heterochromatin in fission yeast

31 March 2020

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MicroRNA biogenesis: coordinated cropping and dicing

31 March 2020

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MicroRNA-directed transcriptional gene silencing in mammalian cells

31 March 2020

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Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals

31 March 2020

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Sequence Relationships among C. elegans, D. melanogaster and Human microRNAs Highlight the Extensive Conservation of microRNAs in Biology

31 March 2020

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Specialization and evolution of endogenous small RNA pathways

31 March 2020

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Plant and animal microRNAs: similarities and differences.

31 March 2020

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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

31 March 2020

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MicroRNA maturation: stepwise processing and subcellular localization

31 March 2020

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MicroRNA genes are transcribed by RNA polymerase II

31 March 2020

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

31 March 2020

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RNA polymerase III transcribes human microRNAs

31 March 2020

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The nuclear RNase III Drosha initiates microRNA processing

31 March 2020

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The Drosha-DGCR8 complex in primary microRNA processing

31 March 2020

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Processing of primary microRNAs by the Microprocessor complex

31 March 2020

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The Microprocessor complex mediates the genesis of microRNAs

31 March 2020

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

31 March 2020

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DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

31 March 2020

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A novel type of RNase III family proteins in eukaryotes

31 March 2020

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Human RNase III is a 160-kDa protein involved in preribosomal RNA processing

31 March 2020

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Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location

31 March 2020

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

31 March 2020

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Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences

31 March 2020

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Processing of intronic microRNAs

31 March 2020

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Primary microRNA transcripts are processed co-transcriptionally.

31 March 2020

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Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

31 March 2020

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Exon tethering in transcription by RNA polymerase II

31 March 2020

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Posttranscriptional crossregulation between Drosha and DGCR8.

31 March 2020

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Intronic microRNA precursors that bypass Drosha processing

31 March 2020

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The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

31 March 2020

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31 March 2020

Mammalian mirtron genes

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A human snoRNA with microRNA-like functions

31 March 2020

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MicroRNA precursors in motion: exportin-5 mediates their nuclear export

31 March 2020

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Nuclear export of microRNA precursors

31 March 2020

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Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

31 March 2020

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Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

31 March 2020

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Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm

31 March 2020

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Exportin-5-mediated nuclear export of eukaryotic elongation factor 1A and tRNA

31 March 2020

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Exportin-5 mediates nuclear export of minihelix-containing RNAs

31 March 2020

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Human let-7 stem-loop precursors harbor features of RNase III cleavage products

31 March 2020

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Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

31 March 2020

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Role for a bidentate ribonuclease in the initiation step of RNA interference

31 March 2020

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

31 March 2020

1 reference

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

31 March 2020

1 reference

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

31 March 2020

1 reference

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

31 March 2020

1 reference

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

31 March 2020

1 reference

Genetic and functional diversification of small RNA pathways in plants

31 March 2020

1 reference

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

31 March 2020

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

31 March 2020

1 reference

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

31 March 2020

1 reference

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

31 March 2020

1 reference

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

31 March 2020

1 reference

The role of PACT in the RNA silencing pathway

31 March 2020

1 reference

The dsRNA protein kinase PKR: virus and cell control

31 March 2020

1 reference

Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening

31 March 2020

1 reference

Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

1 reference

Functional siRNAs and miRNAs Exhibit Strand Bias

31 March 2020

1 reference

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

31 March 2020

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In vitro reconstitution of the human RISC-loading complex

31 March 2020

1 reference

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

31 March 2020

1 reference

A protein sensor for siRNA asymmetry

31 March 2020

1 reference

31 March 2020

RNAi: RISC gets loaded.

1 reference

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

31 March 2020

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

31 March 2020

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Slicer function of Drosophila Argonautes and its involvement in RISC formation

31 March 2020

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

31 March 2020

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Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.

31 March 2020

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Sorting of Drosophila small silencing RNAs

31 March 2020

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Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

31 March 2020

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Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

31 March 2020

1 reference

Argonaute2 is the catalytic engine of mammalian RNAi

31 March 2020

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

31 March 2020

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Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

31 March 2020

1 reference

Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies.

31 March 2020

1 reference

A mammalian microRNA expression atlas based on small RNA library sequencing

31 March 2020

1 reference

miR2Disease: a manually curated database for microRNA deregulation in human disease

31 March 2020

1 reference

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

31 March 2020

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Muscle-specific microRNA miR-206 promotes muscle differentiation

31 March 2020

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Myogenic factors that regulate expression of muscle-specific microRNAs

31 March 2020

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microRNAs join the p53 network--another piece in the tumour-suppression puzzle

31 March 2020

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A microRNA polycistron as a potential human oncogene

31 March 2020

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Widespread microRNA repression by Myc contributes to tumorigenesis

31 March 2020

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Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression

31 March 2020

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SMAD proteins control DROSHA-mediated microRNA maturation

31 March 2020

1 reference

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

31 March 2020

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Posttranscriptional regulation of miRNAs harboring conserved terminal loops.

31 March 2020

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

31 March 2020

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Human embryonic stem cells express a unique set of microRNAs

31 March 2020

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Extensive post-transcriptional regulation of microRNAs and its implications for cancer

31 March 2020

1 reference

Post-transcriptional regulation of the let-7 microRNA during neural cell specification

31 March 2020

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Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

31 March 2020

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Selective blockade of microRNA processing by Lin28

31 March 2020

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A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

31 March 2020

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Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

31 March 2020

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Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules

31 March 2020

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A hexanucleotide element directs microRNA nuclear import.

31 March 2020

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A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

31 March 2020

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Degradation of microRNAs by a family of exoribonucleases in Arabidopsis

31 March 2020

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Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

31 March 2020

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RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex

31 March 2020

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Frequency and fate of microRNA editing in human brain

31 March 2020

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Post-transcriptional regulation of microRNA expression

31 March 2020

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Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors

31 March 2020

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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma

31 March 2020

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A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.

31 March 2020

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let-7 regulates Dicer expression and constitutes a negative feedback loop

31 March 2020

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A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

31 March 2020

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Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

31 March 2020

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A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

31 March 2020

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Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline

31 March 2020

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The small RNA profile during Drosophila melanogaster development

31 March 2020

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A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal

31 March 2020

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Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation.

31 March 2020

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Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline

31 March 2020

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Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene

31 March 2020

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Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

31 March 2020

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Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila

31 March 2020

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A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila

31 March 2020

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Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad.

31 March 2020

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A novel class of small RNAs bind to MILI protein in mouse testes

31 March 2020

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A germline-specific class of small RNAs binds mammalian Piwi proteins

31 March 2020

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A novel class of small RNAs in mouse spermatogenic cells

31 March 2020

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Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

31 March 2020

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A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.

31 March 2020

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MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline

31 March 2020

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Developmentally regulated piRNA clusters implicate MILI in transposon control

31 March 2020

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DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

31 March 2020

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RNA silencing: genomic defence with a slice of pi.

31 March 2020

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zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline

31 March 2020

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Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster

31 March 2020

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Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage

31 March 2020

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The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race

31 March 2020

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An epigenetic role for maternally inherited piRNAs in transposon silencing

31 March 2020

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Characterization of the piRNA Complex from Rat Testes

31 March 2020

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A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice

31 March 2020

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Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends

31 March 2020

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The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.

31 March 2020

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Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

31 March 2020

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The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated.

31 March 2020

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Methylation as a crucial step in plant microRNA biogenesis

31 March 2020

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Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells

31 March 2020

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Endogenous RNA interference provides a somatic defense against Drosophila transposons

31 March 2020

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Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

31 March 2020

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The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster

31 March 2020

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RNA interference directs innate immunity against viruses in adult Drosophila

31 March 2020

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Editor meets silencer: crosstalk between RNA editing and RNA interference

31 March 2020

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DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

31 March 2020

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Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins

31 March 2020

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The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis

31 March 2020

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Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

31 March 2020

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Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets

31 March 2020

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

31 March 2020

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Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain

31 March 2020

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Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

31 March 2020

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Structure of the guide-strand-containing argonaute silencing complex

31 March 2020

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Crystal structure of Argonaute and its implications for RISC slicer activity

31 March 2020

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Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

31 March 2020

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

31 March 2020

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Drosophila PIWI associates with chromatin and interacts directly with HP1a

31 March 2020

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Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

31 March 2020

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Single processing center models for human Dicer and bacterial RNase III

31 March 2020

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Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

31 March 2020

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Crystal structure of human DGCR8 core

31 March 2020

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Heme is involved in microRNA processing

31 March 2020

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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

31 March 2020

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Structural basis for double-stranded RNA processing by Dicer

31 March 2020

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

31 March 2020

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Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA.

31 March 2020

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Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C.

31 March 2020

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12 December 2020

Structure and conserved RNA binding of the PAZ domain

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12 December 2020

The RNA interference proteins and vasa locus are involved in the silencing of retrotransposons in the female germline of Drosophila melanogaster.

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12 December 2020

Reduced accumulation of specific microRNAs in colorectal neoplasia

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12 December 2020

piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells

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12 December 2020

Identifiers

DOI

10.1038/NRM2632

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

432619

1009902558

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432619

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference