Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells. (Q36208555)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21824272%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells (English)

1 reference

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9 February 2020

0 references

4

1 reference

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9 February 2020

author name string

Michael Y Sherman

1

1 reference

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9 February 2020

Le Meng

2

1 reference

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9 February 2020

Martha Stampfer

3

1 reference

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9 February 2020

Julia A Yaglom

5

1 reference

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9 February 2020

publication date

16 September 2011

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9 February 2020

1 reference

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9 February 2020

volume

10

1 reference

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9 February 2020

page(s)

949-961

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9 February 2020

issue

6

1 reference

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TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells

9 February 2020

cites work

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1 October 2017

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Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses

1 October 2017

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1 October 2017

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1 October 2017

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Oncogene-induced senescence pathways weave an intricate tapestry

1 October 2017

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 October 2017

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 October 2017

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Senescence and serration: a new twist to an old tale

1 October 2017

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Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells

1 October 2017

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 October 2017

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 October 2017

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Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair

1 October 2017

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 October 2017

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 October 2017

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Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells.

1 October 2017

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DNA end joining becomes less efficient and more error-prone during cellular senescence

1 October 2017

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The serial cultivation of human diploid cell strains

1 October 2017

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Human epithelial cell immortalization as a step in carcinogenesis

1 October 2017

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1 October 2017

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Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 October 2017

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 October 2017

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1 October 2017

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1 October 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Telomeres shorten during ageing of human fibroblasts

1 October 2017

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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

1 October 2017

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Tumour biology: senescence in premalignant tumours

29 June 2018

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Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

29 June 2018

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Oncogene-induced senescence as an initial barrier in lymphoma development

29 June 2018

1 reference

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Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00736.X

ATR and H2AX cooperate in maintaining genome stability under replication stress

21 January 2018

1 reference

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Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion

21 January 2018

1 reference

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Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression.

21 January 2018

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

21 January 2018

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Executing Cell Senescence

21 January 2018

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Executing cell senescence

21 January 2018

1 reference

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21824272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21824272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HSP72 depletion suppresses gammaH2AX activation by genotoxic stresses via p53/p21 signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21824272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1474-9726.2011.00736.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21824272%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21824272%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference