RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect (Q36026989)

11 August 2017

RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect (English)

1 reference

11 August 2017

6

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15 June 2020

author name string

Chen-Song Zhang

1

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15 June 2020

Qi Liu

2

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15 June 2020

Mengqi Li

3

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15 June 2020

Shu-Yong Lin

4

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15 June 2020

Yongying Peng

5

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15 June 2020

Terytty Yang Li

7

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15 June 2020

Qiang Fu

8

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15 June 2020

Weiping Jia

9

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15 June 2020

Xinjun Wang

10

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15 June 2020

Teng Ma

11

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15 June 2020

Yue Zong

12

1 reference

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15 June 2020

Jiwen Cui

13

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15 June 2020

Chengfei Pu

14

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15 June 2020

Guili Lian

15

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15 June 2020

Huiling Guo

16

1 reference

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15 June 2020

Zhiyun Ye

17

1 reference

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15 June 2020

Sheng-Cai Lin

18

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15 June 2020

publication date

28 July 2015

1 reference

11 August 2017

1 reference

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15 June 2020

volume

25

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15 June 2020

issue

9

1 reference

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15 June 2020

page(s)

1025-1042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26215701%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

15 June 2020

copyright license

start time

28 July 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/cr.2015.90

0 references

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2 October 2017

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LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription

2 October 2017

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2 October 2017

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Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

2 October 2017

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Oxygen sensing by HIF hydroxylases

2 October 2017

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Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

2 October 2017

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2 October 2017

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The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

2 October 2017

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

2 October 2017

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2 October 2017

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

2 October 2017

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Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

2 October 2017

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Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

2 October 2017

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

2 October 2017

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A conserved family of prolyl-4-hydroxylases that modify HIF

2 October 2017

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

2 October 2017

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

2 October 2017

1 reference

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Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

2 October 2017

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

2 October 2017

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

2 October 2017

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

2 October 2017

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Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

2 October 2017

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

2 October 2017

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Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

2 October 2017

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

2 October 2017

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

2 October 2017

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

2 October 2017

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

2 October 2017

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

2 October 2017

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

2 October 2017

1 reference

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

2 October 2017

1 reference

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Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

2 October 2017

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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

2 October 2017

1 reference

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Purification and characterization of hypoxia-inducible factor 1

2 October 2017

1 reference

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

2 October 2017

1 reference

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

2 October 2017

1 reference

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Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4559813

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4559813

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4559813

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4559813

Hypoxic Regulation of Lactate Dehydrogenase A

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCR.2015.90

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26215701

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CR.2015.90

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26215701%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26215701%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26215701%20AND%20SRC:MED&resulttype=core&format=json