Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor (Q24298032)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802534%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor (English)

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13 February 2020

0 references

1

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13 February 2020

author name string

H Xin

2

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13 February 2020

D T Eckert

3

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13 February 2020

J A Brown

4

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13 February 2020

J R Gnarra

5

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13 February 2020

language of work or name

English

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publication date

30 August 2010

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13 February 2020

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13 February 2020

volume

30

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13 February 2020

page(s)

21-31

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issue

1

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

13 February 2020

cites work

1 reference

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Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

19 March 2017

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Mammalian Cdh1/Fzr mediates its own degradation

19 March 2017

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Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

19 March 2017

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RING domain E3 ubiquitin ligases

19 March 2017

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The spindle-assembly checkpoint in space and time

19 March 2017

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The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma

19 March 2017

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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

19 March 2017

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Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

19 March 2017

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Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis

19 March 2017

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Generating specificity and diversity in the transcriptional response to hypoxia

19 March 2017

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The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression

27 September 2017

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VHL loss causes spindle misorientation and chromosome instability.

27 September 2017

1 reference

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Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis

27 September 2017

1 reference

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

27 September 2017

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Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia

27 September 2017

1 reference

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To cell cycle, swing the APC/C.

27 September 2017

1 reference

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The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors

27 September 2017

1 reference

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pVHL and GSK3beta are components of a primary cilium-maintenance signalling network

27 September 2017

1 reference

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Mitotic regulation of the anaphase-promoting complex

27 September 2017

1 reference

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E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis

27 September 2017

1 reference

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Expression of p53 in renal carcinoma cells is independent of pVHL.

27 September 2017

1 reference

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Proline hydroxylation and gene expression

27 September 2017

1 reference

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Synchronization of cell populations in G1/S and G2/M phases of the cell cycle.

27 September 2017

1 reference

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Regulation of transcription and translation by hypoxia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995849

Linking tumor suppression, DNA damage and the anaphase-promoting complex.

27 September 2017

1 reference

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

27 September 2017

1 reference

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Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene

27 September 2017

1 reference

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Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

27 September 2017

1 reference

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The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

27 September 2017

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Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

27 September 2017

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UMD (Universal mutation database): a generic software to build and analyze locus-specific databases

27 September 2017

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pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation

27 September 2017

1 reference

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A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor.

27 September 2017

1 reference

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Regulation of proliferation-survival decisions during tumor cell hypoxia

27 September 2017

1 reference

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The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

27 September 2017

1 reference

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Tumour suppression by the human von Hippel-Lindau gene product

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995849

Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995849

HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.395

Von Hippel-Lindau disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.395

Proteolysis of CDH1 enhances susceptibility to UV radiation-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.395

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.395

Hypoxia inhibits G1/S transition through regulation of p27 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.395

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.395

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802534%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 February 2020

0 references

1 reference

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13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802534%20AND%20SRC:MED&resulttype=core&format=json