Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. (Q40563648)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15104534%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases (English)

1 reference

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27 December 2019

0 references

8

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27 December 2019

7

Wolfgang Jelkmann

1 reference

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27 December 2019

9

Eric Metzen

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27 December 2019

1

Jan H Marxsen

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27 December 2019

author name string

Petra Stengel

2

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27 December 2019

Kathrin Doege

3

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27 December 2019

Pekka Heikkinen

4

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27 December 2019

Terhi Jokilehto

5

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27 December 2019

Thomas Wagner

6

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27 December 2019

language of work or name

English

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publication date

1 August 2004

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27 December 2019

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27 December 2019

volume

381

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27 December 2019

page(s)

761-767

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27 December 2019

issue

Pt 3

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The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

22 September 2017

1 reference

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels

22 September 2017

1 reference

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Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

22 September 2017

1 reference

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

22 September 2017

1 reference

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Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways

22 September 2017

1 reference

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Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells

22 September 2017

1 reference

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Hypoxia-inducible factor and its biomedical relevance

22 September 2017

1 reference

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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

22 September 2017

1 reference

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Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

22 September 2017

1 reference

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Breakthrough of the year. Small RNAs make big splash

22 September 2017

1 reference

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Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

22 September 2017

1 reference

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Transcription. Oxygen sensing gets a second wind

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

A conserved family of prolyl-4-hydroxylases that modify HIF

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Characterization and comparative analysis of the EGLN gene family

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

From Genetically Altered Mice to Integrative Physiology

22 September 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

22 September 2017

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

22 September 2017

1 reference

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HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

22 September 2017

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

22 September 2017

1 reference

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Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

22 September 2017

1 reference

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Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

25 September 2017

1 reference

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Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133886

Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15104534

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15104534

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20040620

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15104534%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15104534%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference