Mitochondrial complex III regulates hypoxic activation of HIF. (Q37064874)

18 August 2017

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title

Mitochondrial complex III regulates hypoxic activation of HIF. (English)

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18 August 2017

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T Klimova

1

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PubMed ID

18219320

18 August 2017

N S Chandel

series ordinal

2

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18 August 2017

25 January 2008

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Cell Death & Differentiation

18 August 2017

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18 August 2017

15

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18 August 2017

660-666

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18 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402307

18 August 2017

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

21 January 2018

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

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Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Complex III releases superoxide to both sides of the inner mitochondrial membrane

21 January 2018

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The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

21 January 2018

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HIF-dependent antitumorigenic effect of antioxidants in vivo

21 January 2018

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

21 January 2018

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21 January 2018

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21 January 2018

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

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HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

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Intracellular diffusion gradients of O2 and ATP.

21 January 2018

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7 January 2021

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

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7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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7 January 2021

The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia

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7 January 2021

Generation of superoxide anion by succinate-cytochrome c reductase from bovine heart mitochondria

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7 January 2021

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4402307

7 January 2021

An out-of-frame cytochrome b gene deletion from a patient with parkinsonism is associated with impaired complex III assembly and an increase in free radical production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402307

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402307

1 reference

PubMed ID

18219320

Dimensions Publication ID

18 August 2017

0 references

1 reference

PubMed ID

18219320