Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation (Q35208812)

7 August 2017

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title

Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation (English)

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7 August 2017

Tracy Criswell

1

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7 August 2017

Konstantin Leskov

2

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7 August 2017

Shigeki Miyamoto

3

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7 August 2017

Guangbin Luo

4

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7 August 2017

David A Boothman

5

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

22

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7 August 2017

37

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7 August 2017

5813-5827

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206680

7 August 2017

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cites work

EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cells

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The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

21 January 2018

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Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer

21 January 2018

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Transcriptional regulation by the AP-1 family of enhancer-binding proteins: a nuclear target for signal transduction

21 January 2018

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Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells

21 January 2018

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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

21 January 2018

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Expression of p53, p21/WAF/CIP, Bcl-2, Bax, Bcl-x, and Bak in radiation-induced apoptosis in testicular germ cell tumor lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Effect of protein kinase C inhibitor (PKCI) on radiation sensitivity and c-fos transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Constitutive NF-kappaB activity influences basal apoptosis and radiosensitivity of head-and-neck carcinoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

JunB negatively regulates AP-1 activity and cell proliferation of malignant mouse keratinocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Radiosensitization by overexpression of the nonphosphorylation form of IkappaB-alpha in human glioma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Purification and characterization of human DNA damage checkpoint Rad complexes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Avian sarcoma virus 17 carries the jun oncogene

21 January 2018

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The p53-Mdm2 module and the ubiquitin system.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Isolation and characterization of fra-2, an additional member of the fos gene family

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

21 January 2018

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Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Apoptosis and radiosensitization of hodgkin cells by proteasome inhibition.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

IkappaBalpha degradation is not a requirement for the X-ray-induced activation of nuclear factor kappaB in normal rat astrocytes and human brain tumour cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Ionizing radiation regulates expression of the c-jun protooncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Role of retinoblastoma gene product in p53-mediated DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

p53 Signaling and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

12-O-tetradecanoylphorbol-13-acetate (TPA)-induced c-Jun N-terminal kinase (JNK) phosphatase renders immortalized or transformed epithelial cells refractory to TPA-inducible JNK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

Phosphorylation of p53 protein in response to ionizing radiation occurs at multiple sites in both normal and DNA-PK deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

In vivo imaging of NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Heat shock inhibits radiation-induced activation of NF-kappaB via inhibition of I-kappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Ionizing radiation activates transcription of the EGR1 gene via CArG elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

IkappaB/NF-kappaB mediated cisplatin resistance in HeLa cells after low-dose gamma-irradiation is associated with altered SODD expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Fas is involved in the p53-dependent apoptotic response to ionizing radiation in mouse testis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Missing pieces in the NF-kappaB puzzle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

E-selectin gene induction by ionizing radiation is independent of cytokine induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Prolonged c-jun expression in irradiated ataxia telangiectasia fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Spatial and temporal control of gene therapy using ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Mechanisms of X-ray-mediated protooncogene c-iun expression in radiation-induced human sarcoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Elevated expression of proto-oncogenes accompany enhanced induction of heat-shock genes after exposure of rat embryos in utero to ionizing irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Regulation of the specific DNA binding function of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Infrequent alterations of the p53 gene in rat skin cancers induced by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Ionizing radiation stimulates octamer factor DNA binding activity in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Inhibition of I kappaB-alpha phosphorylation at serine and tyrosine acts independently on sensitization to DNA damaging agents in human glioma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Stage and tissue-specific expression of fosB during mouse development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Death and decoy receptors and p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Role of p53 family members in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Radiation induction of immediate early genes: effectors of the radiation-stress response.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206680

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206680

1 reference

7 August 2017

1 reference