Atm-deficient mice: a paradigm of ataxia telangiectasia (Q29619532)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=8689683

30 April 2017

main subject

ataxia telangiectasia

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6

Collins F

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author name string

Barlow C

1

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Hirotsune S

2

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Paylor R

3

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Liyanage M

4

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Eckhaus M

5

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Shiloh Y

7

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Crawley JN

8

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Ried T

9

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Tagle D

10

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Wynshaw-Boris A

11

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publication date

12 July 1996

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language of work or name

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30 April 2017

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volume

86

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issue

1

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page(s)

159-71

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Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

30 April 2017

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Radiation-induced cell cycle arrest compromised by p21 deficiency

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Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

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Relative increase of T cells expressing the gamma/delta rather than the alpha/beta receptor in ataxia-telangiectasia

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Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice

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Thymocyte apoptosis induced by p53-dependent and independent pathways

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Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

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Rejoining of double strand breaks in normal human and ataxia-telangiectasia fibroblasts after exposure to 60Co gamma-rays, 241Am alpha-particles or bleomycin

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Murine FGFR-1 is required for early postimplantation growth and axial organization

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Fibroblast growth factor receptor 3 is a negative regulator of bone growth

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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Cancer risks in A-T heterozygotes

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Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

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Predominance of null mutations in ataxia-telangiectasia

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure

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Cell death and the cell cycle: a relationship between transformation and neurodegeneration?

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Breakage of the T cell receptor alpha chain locus in non malignant clones from patients with ataxia telangiectasia

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7 January 2021

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

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Tumor spectrum analysis in p53-mutant mice

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A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture

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Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

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p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

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7 January 2021

The cytogenetics of ataxia telangiectasia

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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Cancer. p53, guardian of the genome

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Enhanced chromosomal response of ataxia-telangiectasia cells to specific types of DNA double-strand breaks

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Characterization of a B-lymphocyte t(2;14) (p11;q32) translocation from an ataxia telangiectasia patient conferring a proliferative advantage on cells in vitro

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Radiosensitivity in ataxia-telangiectasia: a new explanation

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7 January 2021

Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene.

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7 January 2021

Ataxia telangiectasia: An investigation of the repair defect in the cell line AT5BIVA by plasmid reconstitution

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7 January 2021

Chromosome specific paints from a high resolution flow karyotype of the mouse

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Molecular analysis of a t(7;14)(q35;q32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasia

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Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

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The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.

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p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

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Spontaneous cytogenetic abnormalities in lymphocytes from thirteen patients with ataxia telangiectasia

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Molecular analysis of a new translocation, t(X;14)(q28;q11), in premalignancy and in leukaemia associated with ataxia telangiectasia

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7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

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Genomic Organization of the ATM gene

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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7 January 2021

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