NGF deprivation-induced gene expression: after ten years, where do we stand? (Q34286977)

1 August 2017

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title

NGF deprivation-induced gene expression: after ten years, where do we stand? (English)

1 reference

1 August 2017

Robert S Freeman

1

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1 August 2017

Robert L Burch

2

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1 August 2017

Robert J Crowder

3

1 reference

1 August 2017

David J Lomb

4

1 reference

1 August 2017

Matthew C Schoell

5

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1 August 2017

Jennifer A Straub

6

1 reference

1 August 2017

Liang Xie

7

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1 August 2017

1 January 2004

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Progress in Brain Research

1 August 2017

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1 August 2017

146

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1 August 2017

111-126

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The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

The p75 neurotrophin receptor and neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Mitochondrial involvement in the point of no return in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Viktor Hamburger and Rita Levi-Montalcini: the path to the discovery of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Exogenous smac induces competence and permits caspase activation in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Mapping, characterization, and expression analysis of the SM-20 human homologue, c1orf12, and identification of a novel related gene, SCAND2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Mechanisms and Functions of Cell Death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

p21WAF1 induces permanent growth arrest and enhances differentiation, but does not alter apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cell death genes in invertebrates and (maybe) vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by cyanide poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Kainate-induced apoptosis in cultured murine cerebellar granule cells elevates expression of the cell cycle gene cyclin D1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

c-Jun and cyclin D1 proteins as mediators of neuronal death after a focal ischaemic insult.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cell death and the cell cycle: a relationship between transformation and neurodegeneration?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Neurotrophins: roles in neuronal development and function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Role of mitogen- and stress-activated kinases in ischemic injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

How oxygen makes its presence felt

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Neurotrophin signal transduction in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

DESTRUCTION OF THE SYMPATHETIC GANGLIA IN MAMMALS BY AN ANTISERUM TO A NERVE-GROWTH PROTEIN.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Physiology of the neurotrophins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Granule cell apoptosis and protein expression in hippocampal dentate gyrus after forebrain ischemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Immunoreactivity of cyclin D1/cdk4 in neurons and oligodendrocytes after focal cerebral ischemia in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Neuronal apoptosis at the G1/S cell cycle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Increased expression of cyclin D1 in the adult rat brain following kainic acid treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Oxygen sensors and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Evidence for a role of mixed lineage kinases in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin-dependent kinases as potential targets to improve stroke outcome.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin-dependent kinases as a therapeutic target for stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin D1 and Cdk4 protein induction in motor neurons after transient spinal cord ischemia in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Inhibition of protein synthesis prevents cell death in sensory and parasympathetic neurons deprived of neurotrophic factor in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

AP-1 in cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

1 reference

7 January 2021

Upregulation of the pro-apoptotic BH3-only peptide harakiri in spinal neurons of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Characterization of cyclin D1 expression in a rat global model of cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Characterization and comparative analysis of the EGLN gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Cyclin D1 messenger RNA is induced in microglia rather than neurons following transient forebrain ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Therapeutic potential of neurotrophic factors for neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Nerve growth factor and the neurotrophic factor hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946008-1

7 January 2021

10.1016/S0079-6123(03)46008-1

Identifiers

DOI

1 reference

1 August 2017

1 reference