Cyclin-dependent kinases as a therapeutic target for stroke. (Q37445826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10944192%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Cyclin-dependent kinases as a therapeutic target for stroke (English)

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9 November 2019

9

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9 November 2019

author name string

Osuga H

1

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9 November 2019

Osuga S

2

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9 November 2019

Wang F

3

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9 November 2019

Fetni R

4

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9 November 2019

Hogan MJ

5

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9 November 2019

Slack RS

6

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9 November 2019

Hakim AM

7

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9 November 2019

Ikeda JE

8

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9 November 2019

language of work or name

English

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publication date

1 August 2000

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9 November 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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9 November 2019

volume

97

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9 November 2019

issue

18

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9 November 2019

page(s)

10254-10259

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E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

9 November 2019

cites work

1 reference

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23 August 2017

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Ischemic cell death in brain neurons

23 August 2017

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Pathobiology of ischaemic stroke: an integrated view

23 August 2017

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Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

23 August 2017

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Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

23 August 2017

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

23 August 2017

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Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

23 August 2017

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

23 August 2017

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The retinoblastoma protein and cell cycle control

23 August 2017

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The nature, distribution and earliest stages of anoxic-ischaemic nerve cell damage in the rat brain as defined by the optical microscope

23 August 2017

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A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction

23 August 2017

1 reference

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Glutamate neurotoxicity and diseases of the nervous system

23 August 2017

1 reference

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The E2F transcription factor is a cellular target for the RB protein

23 August 2017

1 reference

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Effects of an Rb mutation in the mouse

23 August 2017

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

23 August 2017

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Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle

23 August 2017

1 reference

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Cyclins and their associated cyclin-dependent kinases in the human cell cycle

14 September 2017

1 reference

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Induction of cyclin B and H1 kinase activity in apoptotic PC12 cells

28 September 2017

1 reference

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Signal transduction abnormalities in Alzheimer's disease: evidence of a pathogenic stimuli.

28 September 2017

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Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

26 June 2018

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Cell cycle markers in the hippocampus in Alzheimer's disease.

26 June 2018

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Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol.

26 June 2018

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Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes.

2 September 2018

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Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

2 September 2018

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Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1.

2 September 2018

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Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.

2 September 2018

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Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?

2 September 2018

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Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin D1 immunoreactivity after focal cerebral ischemia in rats.

2 September 2018

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Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

2 September 2018

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Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

2 September 2018

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12 December 2020

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

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12 December 2020

Differences in DNA fragmentation following transient cerebral or decapitation ischemia in rats

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12 December 2020

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

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12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

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12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

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12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

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12 December 2020

Mitotic signaling by beta-amyloid causes neuronal death

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12 December 2020

Identifiers

DOI

10.1073/PNAS.170144197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10944192%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

1 reference

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9 November 2019

1 reference