Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion (Q30537354)

30 September 2017

Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion (English)

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S Zanivan

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author name string

P A J Muller

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30 September 2017

A G Trinidad

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P Timpson

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P V E van den Berghe

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C Nixon

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S A Karim

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P T Caswell

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J E Noll

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C R Coffill

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D P Lane

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K H Vousden

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language of work or name

English

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publication date

14 May 2012

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30 September 2017

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32

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1252-1265

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10

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describes a project that uses

30 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3592945/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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TAp63γ enhances nucleotide excision repair through transcriptional regulation of DNA repair genes

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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.

28 July 2018

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Wild-type p53 controls cell motility and invasion by dual regulation of MET expression

28 July 2018

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Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy

28 July 2018

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p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

28 July 2018

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A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

28 July 2018

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GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration

28 July 2018

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ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization

28 July 2018

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Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells

28 July 2018

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Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions

28 July 2018

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28 July 2018

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MET signalling: principles and functions in development, organ regeneration and cancer

28 July 2018

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

28 July 2018

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Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network.

28 July 2018

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Modulation of the vitamin D3 response by cancer-associated mutant p53

28 July 2018

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Mutant p53 gain-of-function in cancer

28 July 2018

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Mutant p53 drives invasion by promoting integrin recycling

28 July 2018

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Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

28 July 2018

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Mutant p53 mediates survival of breast cancer cells

28 July 2018

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When mutants gain new powers: news from the mutant p53 field.

28 July 2018

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RCP is a human breast cancer-promoting gene with Ras-activating function

28 July 2018

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Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells.

28 July 2018

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

28 July 2018

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Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

28 July 2018

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Signaling networks assembled by oncogenic EGFR and c-Met

28 July 2018

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28 July 2018

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

28 July 2018

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Adherens and tight junctions: structure, function and connections to the actin cytoskeleton

28 July 2018

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The MET receptor tyrosine kinase in invasion and metastasis

28 July 2018

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Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis

28 July 2018

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In-gel digestion for mass spectrometric characterization of proteins and proteomes

28 July 2018

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Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

28 July 2018

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Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

28 July 2018

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Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53

28 July 2018

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Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells

28 July 2018

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Transactivation of the EGR1 gene contributes to mutant p53 gain of function

28 July 2018

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Comparison of the effect of mutant and wild-type p53 on global gene expression

28 July 2018

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Met, metastasis, motility and more

28 July 2018

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Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

28 July 2018

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Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor

28 July 2018

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Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

28 July 2018

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

28 July 2018

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Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

28 July 2018

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Regulation of the c-met proto-oncogene promoter by p53.

28 July 2018

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E-cadherin expression in intestinal epithelium

28 July 2018

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An epithelial scatter factor released by embryo fibroblasts.

28 July 2018

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Detection of epidermal growth factor receptors and E-cadherins in the basolateral membrane of A431 cells by laser scanning fluorescence microscopy

28 July 2018

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

28 July 2018

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Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET

28 July 2018

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28 July 2018

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

28 July 2018

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

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TAp63 induces senescence and suppresses tumorigenesis in vivo

21 January 2018

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Inhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans

21 January 2018

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A direct role for Met endocytosis in tumorigenesis.

21 January 2018

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Epidermal growth factor and hepatocyte growth factor cooperate to enhance cell proliferation, scatter, and invasion in murine mammary epithelial cells

21 January 2018

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Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma.

21 January 2018

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A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

21 January 2018

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PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading

21 January 2018

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

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Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion.

21 January 2018

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Silencing the MET oncogene leads to regression of experimental tumors and metastases

21 January 2018

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Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.

21 January 2018

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microRNA-34 family and treatment of cancers with mutant or wild-type p53 (Review).

26 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592945

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

26 November 2018

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An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

31 March 2020

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Modulation of hepatocyte growth factor-induced scattering of HT29 colon carcinoma cells. Involvement of the MAPK pathway

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22580601

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.148

1 reference

Dimensions Publication ID

30 September 2017

0 references

1 reference

30 September 2017

1 reference