Renaissance of mammalian endogenous RNAi (Q26859171)

language of work or name

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1 August 2014

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588

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PubMed

issue

15

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PubMed

page(s)

2550-6

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A three-dimensional view of the molecular machinery of RNA interference

PubMed

cites work

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Biogenesis of small RNAs in animals

21 January 2018

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PIWI-interacting small RNAs: the vanguard of genome defence

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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The many faces of RNAi

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Specific interference with gene function by double-stranded RNA in early mouse development

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

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Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

21 January 2018

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Structure and conserved RNA binding of the PAZ domain

21 January 2018

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Ribonuclease activity and RNA binding of recombinant human Dicer

21 January 2018

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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

21 January 2018

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Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

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siRNAs can function as miRNAs

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Crystal structure of Argonaute and its implications for RISC slicer activity

21 January 2018

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Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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The response of mammalian cells to double-stranded RNA

21 January 2018

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Detection of foreign RNA: implications for RNAi

21 January 2018

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dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells.

21 January 2018

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Substrate-specific kinetics of Dicer-catalyzed RNA processing

21 January 2018

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Autoinhibition of human dicer by its internal helicase domain

21 January 2018

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Long endogenous dsRNAs can induce complete gene silencing in mammalian cells and primary cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Specific interference with gene expression and gene function mediated by long dsRNA in neural cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Control of specific gene expression in mammalian cells by co-expression of long complementary RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Specific and potent RNA interference in terminally differentiated myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

RNAi factors are present and active in human cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Intracellular localization and routing of miRNA and RNAi pathway components

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Absence of non-specific effects of RNA interference triggered by long double-stranded RNA in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Mili, a mammalian member of piwi family gene, is essential for spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

MicroRNA function is globally suppressed in mouse oocytes and early embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Essential role for Argonaute2 protein in mouse oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Critical roles for Dicer in the female germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Maternal microRNAs are essential for mouse zygotic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

MicroRNA activity is suppressed in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Characterization of Dicer-deficient murine embryonic stem cells.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Endogenous siRNAs and noncoding RNA-derived small RNAs are expressed in adult mouse hippocampus and are up-regulated in olfactory discrimination training

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Retrotransposons regulate host genes in mouse oocytes and preimplantation embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Human L1 retrotransposition: cis preference versus trans complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Biology of mammalian L1 retrotransposons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Antiviral immunity directed by small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Antiviral RNA interference in animals: piecing together the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

An antiviral role for the RNA interference machinery in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

RNA interference is an antiviral defence mechanism in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Induction and suppression of RNA silencing by an animal virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Insect antiviral innate immunity: pathways, effectors, and connections

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Identification of microRNAs of the herpesvirus family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Identification of virus-encoded microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

RNA interference functions as an antiviral immunity mechanism in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Antiviral RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A virus-encoded inhibitor that blocks RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Betanodavirus B2 is an RNA interference antagonist that facilitates intracellular viral RNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Nodamura virus nonstructural protein B2 can enhance viral RNA accumulation in both mammalian and insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

The Ebola virus VP35 protein is a suppressor of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A cellular microRNA mediates antiviral defense in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and Mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Reciprocal inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

Structural basis for double-stranded RNA processing by Dicer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030

The molecular architecture of human Dicer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.05.030