MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells (Q42808496)

7 November 2017

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells (English)

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7 November 2017

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Fabio Mohn

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Witold Filipowicz

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object named as

Witold Filipowicz

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Lasse Sinkkonen

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Tabea Hugenschmidt

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Philipp Berninger

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Dimos Gaidatzis

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Caroline G Artus-Revel

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2 March 2008

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Nature Structural & Molecular Biology

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describes a project that uses

7 November 2017

Dicer +/- line D4

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Dicer -/- line 27H10

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exact match

https://scigraph.springernature.com/pub.10.1038/nsmb.1391

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cites work

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Human embryonic stem cells express a unique set of microRNAs

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Maternal microRNAs are essential for mouse zygotic development

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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

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Characterization of Dicer-deficient murine embryonic stem cells.

31 March 2020

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DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

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A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation

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Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression

31 March 2020

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

31 March 2020

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Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog

31 March 2020

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Lost in transcription: p21 repression, mechanisms, and consequences

31 March 2020

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

31 March 2020

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Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

31 March 2020

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The molecular foundations of the maternal to zygotic transition in the preimplantation embryo

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Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

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A microRNA polycistron as a potential human oncogene

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Global hypomethylation of the genome in XX embryonic stem cells.

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Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

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MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

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Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

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Genomic organization and promoter analysis of the Dnmt3b gene

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Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation

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'Green mice' as a source of ubiquitous green cells.

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Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter

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Lack of homologous sequence-specific DNA methylation in response to stable dsRNA expression in mouse oocytes.

31 March 2020

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The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components

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Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences.

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31 March 2020

Identifiers

DOI

10.1038/NSMB.1391

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7 November 2017

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