Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP (Q24539076)

ribonuclease III activity

GOA release 2020-03-11

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GOA release 2020-03-11

5

Witold Filipowicz

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author name string

Haidi Zhang

1

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Fabrice A Kolb

2

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Vincent Brondani

3

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Eric Billy

Ribonuclease activity and RNA binding of recombinant human Dicer

4

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publication date

1 November 2002

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language of work or name

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21

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issue

21

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page(s)

5875-85

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

24 March 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

24 March 2017

1 reference

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

24 March 2017

1 reference

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Role for a bidentate ribonuclease in the initiation step of RNA interference

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

RNA interference is mediated by 21- and 22-nucleotide RNAs

24 March 2017

1 reference

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24 March 2017

1 reference

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

24 March 2017

1 reference

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A microRNA in a multiple-turnover RNAi enzyme complex

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain

24 March 2017

1 reference

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A species of small antisense RNA in posttranscriptional gene silencing in plants

24 March 2017

1 reference

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

24 March 2017

1 reference

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

7 April 2017

1 reference

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On the role of RNA amplification in dsRNA-triggered gene silencing

7 April 2017

1 reference

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ATP Requirements and Small Interfering RNA Structure in the RNA Interference Pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

RNA hairpins in noncoding regions of human brain and Caenorhabditis elegans mRNA are edited by adenosine deaminases that act on RNA.

7 April 2017

1 reference

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Why do miRNAs live in the miRNP?

27 September 2017

1 reference

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RNAi: nature abhors a double-strand

27 September 2017

1 reference

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RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase

27 September 2017

1 reference

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Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

RNA interference: listening to the sound of silence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase

27 September 2017

1 reference

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Targeted mRNA degradation by double-stranded RNA in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Function, mechanism and regulation of bacterial ribonucleases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

The Nucleoside Triphosphatase and Helicase Activities of Vaccinia Virus NPH-II Are Essential for Virus Replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Maternal effects of the short integument mutation on embryo development in Arabidopsis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

The helicase from hepatitis C virus is active as an oligomer

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

Mutational analysis of a ribonuclease III processing signal

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=131079

29 November 2018

Identifiers

DOI

10.1093/EMBOJ/CDF582

1 reference

1 reference

1 reference

PubMed publication ID

12411505

1 reference