CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53 (Q24303502)

regulation of protein stability

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Calcium response factor

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Transformed mouse 3T3 cell double minute 2

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Tumor suppressor ARF

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6

Roger R Reddel

Roger R

Reddel

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9 December 2023

5

Kazunari Taira

Kazunari

Taira

1 reference

9 December 2023

Md Kamrul Hasan

1

Md Kamrul

Hasan

1 reference

9 December 2023

Tomoko Yaguchi

2

Tomoko

Yaguchi

1 reference

9 December 2023

Takashi Sugihara

3

Takashi

Sugihara

1 reference

9 December 2023

Penmetcha K R Kumar

4

Penmetcha K R

Kumar

1 reference

9 December 2023

Sunil C Kaul

7

Sunil C

Kaul

1 reference

9 December 2023

Renu Wadhwa

8

Renu

Journal of Biological Chemistry

Wadhwa

1 reference

9 December 2023

language of work or name

English

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publication date

4 October 2002

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published in

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volume

277

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page(s)

37765-70

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issue

40

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cites work

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

The tumor suppressor protein p16INK4a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

p19ARF prevents G1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200

inferred from DOI database lookup

7 January 2021

based on heuristic

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204177200