Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA (Q24294915)

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility

GOA release 2020-03-11

6

Andrzej Dziembowski

Andrzej

Dziembowski

1 reference

19 October 2023

Rafal Tomecki

3

Rafal

Tomecki

1 reference

19 October 2023

Torben Heick Jensen

5

Torben Heick

Jensen

1 reference

19 October 2023

Dominik Cysewski

4

Dominik

Cysewski

1 reference

19 October 2023

Michal Lubas

1

Michal

Lubas

1 reference

19 October 2023

Christian K Damgaard

series ordinal

2

author given names

Christian K

author last names

Damgaard

1 reference

19 October 2023

language of work or name

English

0 references

publication date

3 July 2013

0 references

published in

The EMBO Journal

0 references

volume

32

0 references

issue

13

0 references

page(s)

1855-68

0 references

cites work

1 reference

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Dis3-like 1: a novel exoribonuclease associated with the human exosome

19 March 2017

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The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

19 March 2017

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TopHat: discovering splice junctions with RNA-Seq

19 March 2017

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19 March 2017

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The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

19 March 2017

1 reference

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C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing

19 March 2017

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ARED 3.0: the large and diverse AU-rich transcriptome.

19 March 2017

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Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

19 March 2017

1 reference

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

19 March 2017

1 reference

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Cytoplasmic foci are sites of mRNA decay in human cells

19 March 2017

1 reference

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The hDcp2 protein is a mammalian mRNA decapping enzyme

19 March 2017

1 reference

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

19 March 2017

1 reference

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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

19 March 2017

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Functions of the exosome in rRNA, snoRNA and snRNA synthesis

19 March 2017

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Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

19 March 2017

1 reference

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The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation

19 March 2017

1 reference

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Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family

19 March 2017

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

19 March 2017

1 reference

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The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

19 March 2017

1 reference

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Endonucleolytic RNA cleavage by a eukaryotic exosome

19 March 2017

1 reference

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A single subunit, Dis3, is essentially responsible for yeast exosome core activity

19 March 2017

1 reference

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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

19 March 2017

1 reference

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The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

19 March 2017

1 reference

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TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

19 March 2017

1 reference

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Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway

19 March 2017

1 reference

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

19 March 2017

1 reference

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Galaxy: a platform for interactive large-scale genome analysis

7 April 2017

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AU-rich elements: characterization and importance in mRNA degradation

7 April 2017

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The many pathways of RNA degradation

7 April 2017

1 reference

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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

7 April 2017

1 reference

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Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro

27 September 2017

1 reference

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Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

P-bodies and stress granules: possible roles in the control of translation and mRNA degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Elastic coupling between RNA degradation and unwinding by an exoribonuclease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Regulation of cytoplasmic mRNA decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Ways and means of eukaryotic mRNA decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981170

The eukaryotic RNA exosome: same scaffold but variable catalytic subunits

27 September 2017

1 reference

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Conserved RNaseII domain protein functions in cytoplasmic mRNA decay and suppresses Arabidopsis decapping mutant phenotypes

27 September 2017

1 reference

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Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae

27 September 2017

1 reference

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Co-translational mRNA decay in Saccharomyces cerevisiae

27 September 2017

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The control of mRNA decapping and P-body formation.

27 September 2017

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27 September 2017

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27 September 2017

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ARE-mRNA degradation requires the 5'-3' decay pathway.

27 September 2017

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Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control

27 September 2017

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Interaction profiling identifies the human nuclear exosome targeting complex

27 September 2017

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High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay

27 September 2017

1 reference

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Purification and characterization of the Escherichia coli exoribonuclease RNase R. Comparison with RNase II.

30 May 2018

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XRN1: A Major 5' to 3' Exoribonuclease in Eukaryotic Cells.

21 January 2018

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Biochemistry and Function of RNA Exosomes

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Linking mRNA turnover and translation: assessing the polyribosomal association of mRNA decay factors and degradative intermediates.

21 January 2018

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Erratum: Regulation of cytoplasmic mRNA decay

21 January 2018

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mRNP quality control goes regulatory

21 January 2018

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Multifunctional deadenylase complexes diversify mRNA control

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23756462

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and characterization of a Saccharomyces cerevisiae exoribonuclease which yields 5'-mononucleotides by a 5' leads to 3' mode of hydrolysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23756462

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2013.135

1 reference

release_5onesar6orazpecvfxm52ojewq

3465955

Fatcat ID

0 references

3465955

1 reference

1 reference

1 reference