GPCRs: Lipid-Dependent Membrane Receptors That Act as Drug Targets (Q59042560)

April 2022 Public Data File from Crossref

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copyrighted

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April 2022 Public Data File from Crossref

cites work

Seven-transmembrane receptors

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The evolutionarily triumphant G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The structure and function of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Molecular signatures of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structure modeling of all identified G protein-coupled receptors in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Learning from the past: evolution of GPCR functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The state of GPCR research in 2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The 7 TM G-protein-coupled receptor target family

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

G-protein-coupled receptor-focused drug discovery using a target class platform approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

I want a new drug: G-protein-coupled receptors in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Functional assays for screening GPCR targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Orphan G protein-coupled receptors: targets for new therapeutic interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

NOBEL 2012 Chemistry: Studies of a ubiquitous receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane protein biophysics

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Energy landscapes as a tool to integrate GPCR structure, dynamics, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Insights into signaling from the β2-adrenergic receptor structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Molecular modeling of the human serotonin(1A) receptor: role of membrane cholesterol in ligand binding of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane cholesterol stabilizes the human serotonin(1A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The dynamic process of β(2)-adrenergic receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

A monoclonal antibody for G protein-coupled receptor crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structure-function of the G protein-coupled receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structure of the chemokine receptor CXCR1 in phospholipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Stereospecific requirement of cholesterol in the function of the serotonin1A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane lipids in the function of serotonin and adrenergic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Identification of cholesterol binding sites in the serotonin1A receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol modulates the dimer interface of the β₂-adrenergic receptor via cholesterol occupancy sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Regulation of receptor function by cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Role of cholesterol in the function and organization of G-protein coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane cholesterol in the function and organization of G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Uncovering the intimate relationship between lipids, cholesterol and GPCR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

G protein-coupled receptor systems and their lipid environment in health disorders during aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

How cells handle cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

What's so special about cholesterol?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The Effect of Sterol Structure on Membrane Lipid Domains Reveals How Cholesterol Can Induce Lipid Domain Formation†

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Lipid rafts as a membrane-organizing principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Transbilayer organization of membrane cholesterol at low concentrations: Implications in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Lipid sorting in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol: a potential therapeutic target in Leishmania infection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Role of membrane cholesterol in leishmanial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Integrity of the actin cytoskeleton of host macrophages is essential for Leishmania donovani infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Biological membranes: the importance of molecular detail

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Are specific nonannular cholesterol binding sites present in G-protein coupled receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Annular and non-annular binding sites on the (Ca2+ + Mg2+)-ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Annular and nonannular binding sites for cholesterol associated with the nicotinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Lipid-protein interactions in biological membranes: a structural perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Interaction of fatty acids with the calcium-magnesium ion dependent adenosinetriphosphatase from sarcoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The sterol-binding antibiotic nystatin differentially modulates ligand binding of the bovine hippocampal serotonin1A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol modulates the antagonist-binding function of hippocampal serotonin1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane cholesterol oxidation inhibits ligand binding function of hippocampal serotonin(1A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Signaling by the human serotonin(1A) receptor is impaired in cellular model of Smith-Lemli-Opitz Syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The serotonin1A receptor: a representative member of the serotonin receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Membrane organization and function of the serotonin(1A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Is there a role for 5-HT1A agonists in the treatment of depression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Differential effects of cholesterol and 7-dehydrocholesterol on the ligand binding activity of the hippocampal serotonin(1A) receptor: implications in SLOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Differential effects of cholesterol and 7-dehydrocholesterol on ligand binding of solubilized hippocampal serotonin1A receptors: implications in SLOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Differential effects of cholesterol and desmosterol on the ligand binding function of the hippocampal serotonin(1A) receptor: implications in desmosterolosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Effect of capsaicin on ligand binding activity of the hippocampal serotonin1A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Electron crystallography reveals the structure of metarhodopsin I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol-protein interaction: methods and cholesterol reporter molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol and the interaction of proteins with membrane domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The sterol-sensing domain: multiple families, a unique role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Sphingolipids and the formation of sterol-enriched ordered membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Role of sphingolipids in the biogenesis of membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Lipid rafts: at a crossroad between cell biology and physics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Cholesterol Depletion Mimics the Effect of Cytoskeletal Destabilization on Membrane Dynamics of the Serotonin1A Receptor: A zFCS Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a)receptors in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Effect of sphingomyelinase treatment on ligand binding activity of human serotonin1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Metabolic depletion of sphingolipids impairs ligand binding and signaling of human serotonin1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Metabolic depletion of sphingolipids enhances the mobility of the human serotonin1A receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Removal of sphingomyelin headgroup inhibits the ligand binding function of hippocampal serotonin1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Role of glycosphingolipids in the function of human serotonin₁A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Dimerization in GPCR mobility and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Oligomeric forms of G protein-coupled receptors (GPCRs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

The role of dimerisation in the cellular trafficking of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Physiological relevance of GPCR oligomerization and its impact on drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Identification of a serotonin/glutamate receptor complex implicated in psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Organization of higher-order oligomers of the serotonin₁(A) receptor explored utilizing homo-FRET in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Oligomerization of the serotonin(1A) receptor in live cells: a time-resolved fluorescence anisotropy approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Taking care of bystander FRET in a crowded cell membrane environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Theory and application of fluorescence homotransfer to melittin oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Enumeration of oligomerization states of membrane proteins in living cells by homo-FRET spectroscopy and microscopy: theory and application

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

G-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Brain cholesterol in normal and pathological aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Diet-induced elevations in serum cholesterol are associated with alterations in hippocampal lipid metabolism and increased oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023

Strategies to discover unexpected targets for drugs active at G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F143023