Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1) (Q56531047)

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object named as

Barry R O'Keefe

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author name string

Alun Bermingham

1

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Edmund Price

2

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Christophe Marchand

3

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Adel Chergui

4

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Alena Naumova

5

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Emily L Whitson

6

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Lauren R H Krumpe

7

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Ekaterina I Goncharova

8

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Jason R Evans

9

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Tawnya C McKee

10

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Curtis J Henrich

DNA topoisomerases: structure, function, and mechanism

11

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language of work or name

English

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publication date

1 July 2017

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page(s)

2472555217717200

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cites work

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SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity

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Synthesis and biological evaluation of nitrated 7-, 8-, 9-, and 10-hydroxyindenoisoquinolines as potential dual topoisomerase I (Top1)-tyrosyl-DNA phosphodiesterase I (TDP1) inhibitors.

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Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells

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TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs

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Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1

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Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay

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12 December 2020

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The response of eukaryotic topoisomerases to DNA damage

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The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis

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