KDM1A microenvironment, its oncogenic potential, and therapeutic significance. (Q55310228)

1 July 2018

1 reference

8 February 2021

KDM1A microenvironment, its oncogenic potential, and therapeutic significance. (English)

1 reference

1 July 2018

1 reference

28 September 2019

tumor microenvironment

1 reference

8 September 2020

1 reference

8 February 2021

lysine demethylase 1A

object has role

subject heading

object named as

KDM1A

1 reference

Tayaba Ismail

1

1 reference

1 July 2018

Hyun-Kyung Lee

2

1 reference

1 July 2018

Chowon Kim

3

1 reference

1 July 2018

Taejoon Kwon

4

1 reference

1 July 2018

Tae Joo Park

5

1 reference

1 July 2018

Hyun-Shik Lee

6

1 reference

1 July 2018

language of work or name

1 reference

19 June 2018

5 references

1 July 2018

3 April 2019

28 September 2019

8 September 2020

8 February 2021

Epigenetics & Chromatin

5 references

1 July 2018

3 April 2019

28 September 2019

8 September 2020

8 February 2021

11

1 reference

1 July 2018

page(s)

33

1 reference

1 July 2018

issue

1

1 reference

1 July 2018

Creative Commons Attribution 4.0 International

copyright license

4 references

3 April 2019

28 September 2019

8 September 2020

on focus list of Wikimedia project

8 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s13072-018-0203-3

0 references

cites work

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Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer

3 July 2018

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Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.

3 July 2018

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LSD1: biologic roles and therapeutic targeting

3 July 2018

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The growing structural and functional complexity of the LSD1/KDM1A histone demethylase

3 July 2018

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Expression, Purification, and Biochemical Analysis of the LSD1/KDM1A Histone Demethylase

3 July 2018

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An epigenetic view of developmental diseases: new targets, new therapies

3 July 2018

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Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression.

3 July 2018

1 reference

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LSD1 inhibitors: a patent review (2010-2015).

3 July 2018

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Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia

3 July 2018

1 reference

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The histone demethylase LSD1 is a novel oncogene and therapeutic target in oral cancer.

3 July 2018

1 reference

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MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B.

3 July 2018

1 reference

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Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation

3 July 2018

1 reference

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Lysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones

3 July 2018

1 reference

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Global histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?

3 July 2018

1 reference

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Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.

3 July 2018

1 reference

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A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC.

3 July 2018

1 reference

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Synergistic targeted therapy for acute promyelocytic leukaemia: a model of translational research in human cancer.

3 July 2018

1 reference

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A Systematic Review of Histone Lysine-Specific Demethylase 1 and Its Inhibitors

3 July 2018

1 reference

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Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer

3 July 2018

1 reference

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KDM1 class flavin-dependent protein lysine demethylases

3 July 2018

1 reference

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Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Relationship between LSD1 expression and E-cadherin expression in prostate cancer

3 July 2018

1 reference

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Androgen receptor epigenetics.

3 July 2018

1 reference

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Chromatin regulation: how complex does it get?

3 July 2018

1 reference

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Androgens and androgen receptor signaling in prostate tumorigenesis.

3 July 2018

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Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

3 July 2018

1 reference

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Long noncoding RNA HOTAIR involvement in cancer

3 July 2018

1 reference

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High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

High expression of the histone demethylase LSD1 associates with cancer cell proliferation and unfavorable prognosis in tongue cancer

3 July 2018

1 reference

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TLX: A master regulator for neural stem cell maintenance and neurogenesis

3 July 2018

1 reference

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Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The nucleosome remodeling and deacetylase complex in development and disease

3 July 2018

1 reference

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Breast cancer: major risk factors and recent developments in treatment

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Differential Properties of Transcriptional Complexes Formed by the CoREST Family

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells

3 July 2018

1 reference

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Long noncoding RNAs: emerging stars in gene regulation, epigenetics and human disease.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Diversity of two forms of DNA methylation in the brain.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

3 July 2018

1 reference

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miR-329 suppresses the growth and motility of neuroblastoma by targeting KDM1A.

3 July 2018

1 reference

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The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma

3 July 2018

1 reference

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The histone demethylase LSD1/KDM1A promotes the DNA damage response

3 July 2018

1 reference

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Breast cancer statistics, 2013.

3 July 2018

1 reference

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The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells

3 July 2018

1 reference

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The roles of LSD1-mediated epigenetic modifications in maintaining the pluripotency of bladder cancer stem cells

3 July 2018

1 reference

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Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].

3 July 2018

1 reference

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LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer

3 July 2018

1 reference

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Epigenetic regulation of EMT: the Snail story

3 July 2018

1 reference

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Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin

3 July 2018

1 reference

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A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes

3 July 2018

1 reference

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Posttranslational modifications of the histone 3 tail and their impact on the activity of histone lysine demethylases in vitro

3 July 2018

1 reference

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Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

3 July 2018

1 reference

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Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

3 July 2018

1 reference

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Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes

3 July 2018

1 reference

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The histone LSD1 demethylase in stemness and cancer transcription programs

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer

3 July 2018

1 reference

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Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

3 July 2018

1 reference

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3 July 2018

The NuRD architecture

1 reference

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Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential.

3 July 2018

1 reference

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Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Epigenetic regulation by long noncoding RNAs

3 July 2018

1 reference

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Histone lysine methylation dynamics: establishment, regulation, and biological impact

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

3 July 2018

1 reference

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The emerging role of histone lysine demethylases in prostate cancer

3 July 2018

1 reference

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Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Breaking the LSD1/KDM1A addiction: therapeutic targeting of the epigenetic modifier in AML.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer

3 July 2018

1 reference

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Molecular mechanisms and potential functions of histone demethylases

3 July 2018

1 reference

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Role of epigenetics in cancer health disparities

3 July 2018

1 reference

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Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine methylation: beyond histones

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

3 July 2018

1 reference

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Histone modifiers in cancer: friends or foes?

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The different roles of ER subtypes in cancer biology and therapy

3 July 2018

1 reference

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Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The CW domain, a new histone recognition module in chromatin proteins

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Modern approaches to treating acute promyelocytic leukemia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Dynamics of histone lysine methylation: structures of methyl writers and erasers

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Aberrant epigenetic landscape in cancer: how cellular identity goes awry

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Structural insights into histone lysine demethylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Structural insight into the zinc finger CW domain as a histone modification reader

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Long noncoding RNA as modular scaffold of histone modification complexes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine methylation regulates E2F1-induced cell death

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Genetic alterations and changes in expression of histone demethylases in prostate cancer.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Histone demethylase LSD1 regulates neural stem cell proliferation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Epithelial-mesenchymal transitions in development and disease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

A novel mammalian flavin-dependent histone demethylase

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The ZNF217 oncogene is a candidate organizer of repressive histone modifiers

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The transcriptional corepressor CtBP: a foe of multiple tumor suppressors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

ZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Androgen regulation of the androgen receptor coregulators

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Transrepressive function of TLX requires the histone demethylase LSD1.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The emerging functions of histone demethylases

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

LSD1 and the chemistry of histone demethylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

p53 is regulated by the lysine demethylase LSD1

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Carcinogen-induced histone alteration in normal human mammary epithelial cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Opposing LSD1 complexes function in developmental gene activation and repression programmes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Transcriptional regulation by C-terminal binding proteins

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Chromatin modifications and their function

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Crystal structure of human histone lysine-specific demethylase 1 (LSD1).

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Complex networks orchestrate epithelial-mesenchymal transitions

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Regulation of LSD1 histone demethylase activity by its associated factors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Coordinated histone modifications mediated by a CtBP co-repressor complex

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

CoREST is an integral component of the CoREST- human histone deacetylase complex

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Selective estrogen receptor modulators: clinical spectrum

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

An overview of epithelio-mesenchymal transformation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

High expression of lysine-specific demethylase 1 correlates with poor prognosis of patients with esophageal squamous cell carcinoma.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Long noncoding RNA and epigenomics.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Crystal structure and mechanism of human lysine-specific demethylase-1.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6006565

Transcriptional regulation by TAL1: a link between epigenetic modifications and erythropoiesis

12 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29921310

12 December 2020

inferred from PubMed ID database lookup

LSD1 and pluripotency: A new player in the network

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29921310

12 December 2020

inferred from PubMed ID database lookup

Positive expression of LSD1 and negative expression of E-cadherin correlate with metastasis and poor prognosis of colon cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29921310

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/S13072-018-0203-3

1 reference

1 July 2018

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13072-018-0203-3

Fatcat ID

release_wm5cg7mnhvc2xg54hr4a5gxmgi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wm5cg7mnhvc2xg54hr4a5gxmgi

24 November 2022

mapped directly with Wikidata item

PMCID

6006565

1 reference

1 July 2018

PubMed ID

29921310

1 reference

1 July 2018