Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners. (Q36639638)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22533360%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners (English)

1 reference

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30 January 2020

1 reference

1

1 reference

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30 January 2020

5

Dewey G McCafferty

1 reference

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30 January 2020

author name string

Michelle D Larrea

series ordinal

2

1 reference

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30 January 2020

Jeff S Jasper

series ordinal

3

1 reference

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30 January 2020

Donald P McDonnell

series ordinal

4

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30 January 2020

publication date

10 May 2012

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30 January 2020

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30 January 2020

volume

7

1 reference

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30 January 2020

issue

7

1 reference

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30 January 2020

page(s)

1221-1231

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Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

30 January 2020

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Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

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Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

30 September 2017

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Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes

30 September 2017

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Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency

30 September 2017

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In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.

30 September 2017

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Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1.

30 September 2017

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A novel mammalian flavin-dependent histone demethylase

30 September 2017

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The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

30 September 2017

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Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

30 September 2017

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Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A

30 September 2017

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p53 is regulated by the lysine demethylase LSD1

30 September 2017

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Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine

30 September 2017

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Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

30 September 2017

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The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners

30 September 2017

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Opposing LSD1 complexes function in developmental gene activation and repression programmes

30 September 2017

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trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.

30 September 2017

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Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors

30 September 2017

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Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.

28 June 2018

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Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype

20 September 2018

1 reference

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Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

20 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22533360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB300108C

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22533360%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22533360%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference