An epigenetic view of developmental diseases: new targets, new therapies (Q38879426)

7 September 2017

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title

An epigenetic view of developmental diseases: new targets, new therapies (English)

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7 September 2017

Pei Xie

1

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7 September 2017

Li-Qun Zang

series ordinal

2

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7 September 2017

Xue-Kun Li

series ordinal

3

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7 September 2017

Qiang Shu

series ordinal

4

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7 September 2017

29 June 2016

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World Journal of Pediatrics

7 September 2017

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7 September 2017

12

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7 September 2017

291-297

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7 September 2017

3

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https://scigraph.springernature.com/pub.10.1007/s12519-016-0020-3

7 September 2017

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Histone methylations in heart development, congenital and adult heart diseases

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Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

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Neuronal activity modifies the DNA methylation landscape in the adult brain

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

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Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

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N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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The story of Rett syndrome: from clinic to neurobiology

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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

21 January 2018

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Synaptic, transcriptional and chromatin genes disrupted in autism

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The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

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Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum

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Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum

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Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

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Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum

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Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage

21 January 2018

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Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

21 January 2018

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DNA methylation status of NKX2-5, GATA4 and HAND1 in patients with tetralogy of fallot

21 January 2018

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Maternal global methylation status and risk of congenital heart diseases

21 January 2018

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Congenital heart defects and biomarkers of methylation in children: a case-control study

21 January 2018

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Polycomb repressive complex 2 regulates normal development of the mouse heart

21 January 2018

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De novo mutations in histone-modifying genes in congenital heart disease.

21 January 2018

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m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells

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N6-methyladenosine marks primary microRNAs for processing

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m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency

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Variation in FTO contributes to childhood obesity and severe adult obesity

21 January 2018

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

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Inactivation of the Fto gene protects from obesity

21 January 2018

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Overexpression of Fto leads to increased food intake and results in obesity

21 January 2018

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Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

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The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

21 January 2018

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RNA-methylation-dependent RNA processing controls the speed of the circadian clock

21 January 2018

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Analytical tools and current challenges in the modern era of neuroepigenomics

21 January 2018

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The emerging field of neuroepigenetics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12519-016-0020-3

Seeking a roadmap toward neuroepigenetics

21 January 2018

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Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27351564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27351564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27351564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12519-016-0020-3

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference