Gene expression regulatory networks in Trypanosoma brucei: insights into the role of the mRNA-binding proteome. (Q53683724)

17 May 2018

title

Gene expression regulatory networks in Trypanosoma brucei: insights into the role of the mRNA-binding proteome. (English)

1 reference

17 May 2018

retrotransposon hot spot protein 4 (RHS4), putative

main subject

Trypanosoma brucei

0 references

1 reference

5 February 2019

1 reference

5 February 2019

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pumilio/PUF RNA binding protein 9

5 February 2019

1 reference

5 February 2019

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cyclin-like F-box protein 2

5 February 2019

1 reference

5 February 2019

mitochondrial RNA binding complex 1 subunit

1 reference

5 February 2019

1 reference

5 February 2019

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ZFP family member, putative

5 February 2019

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zinc finger CCCH domain-containing protein 6, putative

5 February 2019

1 reference

Histone RNA hairpin-binding protein RNA-binding domain containing protein, putative

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

mitochondrial RNA binding complex 1 subunit

1 reference

Histone RNA hairpin-binding protein RNA-binding domain containing protein, putative

5 February 2019

1 reference

General negative regulator of transcription subunit 5

5 February 2019

1 reference

5 February 2019

1 reference

Present in the outer mitochondrial membrane proteome 24

5 February 2019

1 reference

Polynucleotide adenylyltransferase 1

5 February 2019

1 reference

5 February 2019

1 reference

Double RNA binding domain protein 6A

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

60S ribosomal protein L4

1 reference

Zinc finger CCCH domain-containing protein 8

5 February 2019

1 reference

Double RNA binding domain protein 7

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

snoRNP protein GAR1, putative

1 reference

5 February 2019

1 reference

Eukaryotic translation initiation factor 3 subunit 4

5 February 2019

1 reference

DNA/RNA-binding protein Alba 4

5 February 2019

1 reference

DNA/RNA-binding protein Alba 3

5 February 2019

1 reference

5 February 2019

1 reference

ATP-dependent RNA helicase, putative

5 February 2019

1 reference

5 February 2019

1 reference

'Cold-shock' DNA-binding domain containing protein, putative

5 February 2019

1 reference

5 February 2019

1 reference

zinc finger CCCH domain containing protein 11

5 February 2019

1 reference

Eukaryotic translation initiation factor 4 gamma 1

5 February 2019

1 reference

zinc finger CCCH domain containing protein 12

5 February 2019

1 reference

zinc finger CCCH domain containing protein 13

5 February 2019

1 reference

5 February 2019

1 reference

MRB1 complex subunit MRB3010

5 February 2019

1 reference

Pre-mRNA polyadenylation factor FIP1

5 February 2019

1 reference

nucleolar RNA helicase II, putative

5 February 2019

1 reference

5 February 2019

CCR4-associated factor 1

1 reference

kinetoplastid-specific phospho-protein phosphatase, putative

5 February 2019

1 reference

Pumilio homology domain family member 4

5 February 2019

1 reference

ccr4-not transcription complex subunit 2

5 February 2019

1 reference

Polyadenylation mediator complex protein PAMC2, putative

5 February 2019

1 reference

Eukaryotic translation initiation factor 4E-4

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

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5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

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zinc finger ccch domain-containing protein 14

5 February 2019

1 reference

eukaryotic translation initiation factor 3 subunit 7

5 February 2019

1 reference

RNA-binding protein 42 (RNA-binding motif protein 42)

5 February 2019

1 reference

5 February 2019

protein mkt1, putative

1 reference

5 February 2019

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5 February 2019

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40S ribosomal protein S16, putative

5 February 2019

1 reference

40S ribosomal protein S16, putative

5 February 2019

1 reference

5 February 2019

1 reference

60S ribosomal protein L7, putative

5 February 2019

1 reference

60S ribosomal protein L7, putative

5 February 2019

1 reference

60S ribosomal protein L7, putative

5 February 2019

1 reference

5 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

Nucleolar protein 168

1 reference

6 February 2019

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pyrroline-5-carboxylate reductase, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Nitroreductase family, putative

6 February 2019

1 reference

Flagellar attachment zone protein 10

6 February 2019

1 reference

6 February 2019

1 reference

'Cold-shock' DNA-binding domain containing protein, putative

6 February 2019

1 reference

immunodominant antigen, putative

6 February 2019

1 reference

pumilio/PUF RNA binding protein 5

6 February 2019

1 reference

6 February 2019

5'-3' exoribonuclease A

1 reference

Double RNA binding domain protein 12

6 February 2019

1 reference

deoxyribose-phosphate aldolase, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

RNA-binding protein 33 (RNA-binding motif protein 33)

6 February 2019

1 reference

60S ribosomal protein L7a, putative

6 February 2019

1 reference

60S ribosomal protein L7a, putative

6 February 2019

1 reference

6 February 2019

1 reference

ATP-dependent RNA helicase DBP2B, putative

6 February 2019

1 reference

CCR4-NOT transcription complex subunit 11

6 February 2019

1 reference

RNA-binding protein RBP10, putative

6 February 2019

1 reference

6 February 2019

1 reference

Eukaryotic translation initiation factor 4 gamma 5

6 February 2019

1 reference

PAB1-binding protein , putative

6 February 2019

1 reference

eukaryotic translation initiation factor 4 gamma 3

6 February 2019

1 reference

Stumpy formation signalling pathway protein, putative

6 February 2019

1 reference

Eukaryotic initiation factor 4A-1

6 February 2019

1 reference

nucleolar RNA binding protein, putative

6 February 2019

1 reference

40S ribosomal protein S3, putative

6 February 2019

1 reference

GRAM domain containing protein, putative

6 February 2019

1 reference

6 February 2019

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Double RNA binding domain protein 3

6 February 2019

1 reference

6 February 2019

Lsm12 protein, putative

1 reference

6 February 2019

chaperone protein DnaJ, putative

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Zinc finger CCCH domain-containing protein 48

6 February 2019

1 reference

6 February 2019

1 reference

polyadenylate-binding protein 2

6 February 2019

1 reference

4E-interacting protein, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

ATP-dependent DEAD/H RNA helicase, putative

6 February 2019

1 reference

Pentatricopeptide repeat protein (PPR), putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

KKT-interacting protein 9

1 reference

6 February 2019

1 reference

NLI interacting factor-like phosphatase, putative

6 February 2019

1 reference

40S ribosomal protein S6, putative

6 February 2019

1 reference

40S ribosomal protein S6, putative

6 February 2019

1 reference

pumillio/PUF RNA binding protein 3

6 February 2019

1 reference

ATP-dependent RNA helicase SUB2, putative

6 February 2019

1 reference

40S ribosomal proteins S11, putative

6 February 2019

1 reference

6 February 2019

1 reference

elongation factor 1-alpha

6 February 2019

1 reference

elongation factor 1-alpha

6 February 2019

1 reference

elongation factor 1-alpha

6 February 2019

1 reference

nuclear transport factor 2 (ntf2) domain- containing protein

6 February 2019

1 reference

6 February 2019

1 reference

U2 splicing auxiliary factor, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

ribosomal protein L18, putative

6 February 2019

1 reference

40S ribosomal protein S3A, putative

6 February 2019

1 reference

40S ribosomal protein S3A, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

pumillo RNA binding protein PUF1

1 reference

6 February 2019

1 reference

6 February 2019

eukaryotic translation initiation factor 3 subunit l

1 reference

6 February 2019

1 reference

40S ribosomal protein S18, putative

6 February 2019

1 reference

40S ribosomal protein S10, putative

6 February 2019

1 reference

40S ribosomal protein S10, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

universal minicircle sequence binding protein 2

1 reference

universal minicircle sequence binding protein 1

6 February 2019

1 reference

eukaryotic translation initiation factor 3 subunit c

6 February 2019

1 reference

CCR4-NOT transcription complex subunit 10, putative

6 February 2019

1 reference

flagellum targeting protein kharon1, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

RGG-containing protein 2

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

40S ribosomal protein S3, putative

6 February 2019

1 reference

pumilio/PUF RNA binding protein 6

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

pumilio/PUF RNA binding protein 2

6 February 2019

1 reference

Zinc finger CCCH domain-containing protein 37

6 February 2019

1 reference

Zinc finger CCCH domain-containing protein 38

6 February 2019

1 reference

6 February 2019

1 reference

RNA-binding protein 29, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

nuclear segregation protein, putative

1 reference

ATP-dependent RNA helicase HEL67

6 February 2019

1 reference

6 February 2019

1 reference

Zinc finger CCCH domain-containing protein 39

6 February 2019

1 reference

Zinc finger CCCH domain-containing protein 40

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

RNA-binding protein, UBP1

6 February 2019

1 reference

RNA-binding protein, UBP2

6 February 2019

1 reference

6 February 2019

1 reference

Suppressor of clathrin deficiency 6, putative

6 February 2019

1 reference

mitochondrial RNA binding protein 1

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Eukaryotic translation initiation factor 4E-1

6 February 2019

1 reference

eukaryotic peptide chain release factor subunit 1, putative

6 February 2019

1 reference

HIT zinc finger, putative

6 February 2019

1 reference

RNA-binding protein 34, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

40S ribosomal protein S4, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Eukaryotic translation initiation factor 1, putative

6 February 2019

1 reference

RNA-binding protein 38, putative

6 February 2019

1 reference

6 February 2019

eukaryotic release factor 3, putative

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

60S ribosomal protein L28, putative

6 February 2019

1 reference

40S ribosomal protein S5, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

pumilio/PUF RNA binding protein 10, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

cell cycle sequence binding phosphoprotein (RBP33), putative

1 reference

zinc finger CCCH domain containing protein 44

6 February 2019

1 reference

6 February 2019

1 reference

ribosomal protein S26, putative

6 February 2019

1 reference

6 February 2019

eukaryotic translation initiation factor 4 gamma 4

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

40S ribosomal protein SA, putative

6 February 2019

1 reference

pumillio/PUF RNA binding protein 11

6 February 2019

1 reference

40S ribosomal protein SA, putative

6 February 2019

1 reference

receptor for activated C kinase 1

6 February 2019

1 reference

Eukaryotic translation initiation factor 4E-3

6 February 2019

1 reference

R3H domain containing protein, putative

6 February 2019

1 reference

6 February 2019

1 reference

Present in the outer mitochondrial membrane proteome 17

6 February 2019

1 reference

mitochondrial RNA binding protein 2

6 February 2019

1 reference

Pab1p-dependent poly(A) ribonuclease subunit, putative

6 February 2019

1 reference

nuclear RNA binding domain 1

6 February 2019

1 reference

nuclear RNA binding domain 2

6 February 2019

1 reference

Double RNA binding domain protein 18

6 February 2019

1 reference

Double RNA-binding domain containing protein 4

6 February 2019

1 reference

Staphylococcal nuclease homologue/Tudor domain containing protein, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

zinc finger protein 2

1 reference

survival of motor neuron (SMN)-like protein

6 February 2019

1 reference

Zinc finger protein, C3H1 type-like

6 February 2019

1 reference

7 February 2019

4

Jörg D Hoheisel

1 reference

17 May 2018

author name string

Smiths Lueong

1

1 reference

17 May 2018

Clementine Merce

2

1 reference

17 May 2018

Bernd Fischer

3

1 reference

17 May 2018

Esteban D Erben

5

1 reference

17 May 2018

language of work or name

English

0 references

publication date

10 March 2016

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17 May 2018

published in

Molecular Microbiology

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17 May 2018

volume

100

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17 May 2018

issue

3

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17 May 2018

page(s)

457-471

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17 May 2018

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

cites work

1 reference

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

21 January 2018

1 reference

The mRNAs associated to a zinc finger protein from Trypanosoma cruzi shift during stress conditions.

21 January 2018

1 reference

Trypanosoma brucei PUF9 regulates mRNAs for proteins involved in replicative processes over the cell cycle

21 January 2018

1 reference

21 January 2018

1 reference

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

21 January 2018

1 reference

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs

21 January 2018

1 reference

The F-box protein CFB2 is required for cytokinesis of bloodstream-form Trypanosoma brucei

21 January 2018

1 reference

The Trypanosoma brucei zinc finger protein ZC3H18 is involved in differentiation

21 January 2018

1 reference

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

21 January 2018

1 reference

RNA-binding proteins in Mendelian disease.

21 January 2018

1 reference

System-wide identification of RNA-binding proteins by interactome capture.

21 January 2018

1 reference

The regulation of trypanosome gene expression by RNA-binding proteins

21 January 2018

1 reference

Import of fructose bisphosphate aldolase into the glycosomes of Trypanosoma brucei

21 January 2018

1 reference

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

1 reference

The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism

21 January 2018

1 reference

Is there a classical nonsense-mediated decay pathway in trypanosomes?

21 January 2018

1 reference

The two eIF4A helicases in Trypanosoma brucei are functionally distinct.

21 January 2018

1 reference

The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation

21 January 2018

1 reference

Post-transcriptional regulation of the trypanosome heat shock response by a zinc finger protein

21 January 2018

1 reference

The CAF1-NOT complex of trypanosomes

21 January 2018

1 reference

A genome-wide tethering screen reveals novel potential post-transcriptional regulators in Trypanosoma brucei

21 January 2018

1 reference

The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes

21 January 2018

1 reference

The roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation

21 January 2018

1 reference

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

21 January 2018

1 reference

The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties.

21 January 2018

1 reference

Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog

21 January 2018

1 reference

RNA-binding proteins and post-transcriptional gene regulation

21 January 2018

1 reference

Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation-enriched CCCH protein.

21 January 2018

1 reference

A novel CCCH protein which modulates differentiation of Trypanosoma brucei to its procyclic form

21 January 2018

1 reference

The 14-3-3 proteins of Trypanosoma brucei function in motility, cytokinesis, and cell cycle

21 January 2018

1 reference

snRNA-specific role of SMN in trypanosome snRNP biogenesis in vivo

21 January 2018

1 reference

The trypanosome Pumilio domain protein PUF5.

21 January 2018

1 reference

Depletion of the Trypanosome Pumilio domain protein PUF2 or of some other essential proteins causes transcriptome changes related to coding region length

21 January 2018

1 reference

The DRBD13 RNA binding protein is involved in the insect-stage differentiation process of Trypanosoma brucei

21 January 2018

1 reference

Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae

21 January 2018

1 reference

Polysomes of Trypanosoma brucei: Association with Initiation Factors and RNA-Binding Proteins

21 January 2018

1 reference

Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein.

21 January 2018

1 reference

Differential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools

21 January 2018

1 reference

The RNA-binding protein repertoire of embryonic stem cells.

21 January 2018

1 reference

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

21 January 2018

1 reference

A model for random sampling and estimation of relative protein abundance in shotgun proteomics

21 January 2018

1 reference

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

21 January 2018

1 reference

Characterization of the Crithidia fasciculata mRNA cycling sequence binding proteins

21 January 2018

1 reference

Construction of a reading frame-independent yeast two-hybrid vector system for site-specific recombinational cloning and protein interaction screening

21 January 2018

1 reference

Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery

21 January 2018

1 reference

Conserved mRNA-binding proteomes in eukaryotic organisms.

21 January 2018

1 reference

Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome

21 January 2018

1 reference

Global analysis of yeast mRNPs

21 January 2018

1 reference

Presence of a poly(A) binding protein and two proteins with cell cycle-dependent phosphorylation in Crithidia fasciculata mRNA cycling sequence binding protein II.

21 January 2018

1 reference

High-throughput yeast two-hybrid screening of complex cDNA libraries

21 January 2018

1 reference

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

21 January 2018

1 reference

21 January 2018

1 reference

Paraspeckle formation during the biogenesis of long non-coding RNAs

21 January 2018

1 reference

Global identification of conserved post-transcriptional regulatory programs in trypanosomatids

21 January 2018

1 reference

The Trypanosoma brucei CCCH zinc finger proteins ZC3H12 and ZC3H13.

21 January 2018

1 reference

Advancing Trypanosoma brucei genome annotation through ribosome profiling and spliced leader mapping

21 January 2018

1 reference

Identification and stage-specific association with the translational apparatus of TbZFP3, a CCCH protein that promotes trypanosome life-cycle development.

21 January 2018

1 reference

The eIF4E subunits of two distinct trypanosomatid eIF4F complexes are subjected to differential post-translational modifications associated to distinct growth phases in culture.

21 January 2018

1 reference

Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons

21 January 2018

1 reference

PUF proteins: repression, activation and mRNA localization

21 January 2018

1 reference

Altered ribostasis: RNA-protein granules in degenerative disorders

21 January 2018

1 reference

A role for Q/N-rich aggregation-prone regions in P-body localization.

21 January 2018

1 reference

DERA is the human deoxyribose phosphate aldolase and is involved in stress response

21 January 2018

1 reference

A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes.

21 January 2018

1 reference

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

21 January 2018

1 reference

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

21 January 2018

1 reference

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

21 January 2018

1 reference

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

21 January 2018

1 reference

InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic

21 January 2018

1 reference

MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

21 January 2018

1 reference

ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation

21 January 2018

1 reference

Proteome-Wide Search Reveals Unexpected RNA-Binding Proteins in Saccharomyces cerevisiae

21 January 2018

1 reference

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages.

21 January 2018

1 reference

GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes.

21 January 2018

1 reference

The post-transcriptional trans-acting regulator, TbZFP3, co-ordinates transmission-stage enriched mRNAs in Trypanosoma brucei.

21 January 2018

1 reference

The polysome-associated proteins Scp160 and Bfr1 prevent P body formation under normal growth conditions

21 January 2018

1 reference

Expression of the RNA recognition motif protein RBP10 promotes a bloodstream-form transcript pattern in Trypanosoma brucei

21 January 2018

1 reference

Evolutionary conservation and diversification of the translation initiation apparatus in trypanosomatids.

21 January 2018

1 reference

A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways.

21 January 2018

1 reference

Functional analysis of Trypanosoma brucei PUF1

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/MMI.13328

1 reference

17 May 2018

1 reference

17 May 2018