Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci. (Q48089880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29412141%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci (English)

1 reference

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14 March 2020

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1 reference

10

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14 March 2020

Matthias Thurner

1

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14 March 2020

Martijn van de Bunt

2

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14 March 2020

Vibe Nylander

5

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14 March 2020

Amanda J Bennett

6

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14 March 2020

Carla Burrows

9

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14 March 2020

Anna Gloyn

14

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14 March 2020

Mark McCarthy

15

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14 March 2020

author name string

Jason M Torres

3

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14 March 2020

Anubha Mahajan

4

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14 March 2020

Kyle J Gaulton

7

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14 March 2020

Amy Barrett

8

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14 March 2020

Robert Lowe

11

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14 March 2020

Stephan Beck

12

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14 March 2020

Vardhman K Rakyan

13

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14 March 2020

language of work or name

English

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publication date

7 February 2018

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14 March 2020

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14 March 2020

volume

7

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describes a project that uses

14 March 2020

ggplot2

object named as

ggplot2

2 references

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=5828664

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

14 June 2018

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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus

14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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Bayesian refinement of association signals for 14 loci in 3 common diseases

14 June 2018

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Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes

14 June 2018

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14 June 2018

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14 June 2018

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ChromHMM: automating chromatin-state discovery and characterization

14 June 2018

1 reference

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14 June 2018

1 reference

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FLASH: fast length adjustment of short reads to improve genome assemblies

14 June 2018

1 reference

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A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

14 June 2018

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Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Mapping and analysis of chromatin state dynamics in nine human cell types

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

FIMO: scanning for occurrences of a given motif

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

LocusZoom: regional visualization of genome-wide association scan results

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

A map of open chromatin in human pancreatic islets

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

The Sequence Alignment/Map format and SAMtools

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Fast and accurate short read alignment with Burrows-Wheeler transform

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

DNA methylation profiling of human chromosomes 6, 20 and 22

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Adjusting batch effects in microarray expression data using empirical Bayes methods

14 June 2018

1 reference

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The human genome browser at UCSC

14 June 2018

1 reference

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Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

DNA-binding factors shape the mouse methylome at distal regulatory regions

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828664

14 August 2018

Identifiers

DOI

10.7554/ELIFE.31977

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29412141%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29412141%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference