Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo. (Q47846970)

6 February 2018

title

Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo. (English)

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6 February 2018

author name string

Hiroshi Takuma

1

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6 February 2018

Takami Tomiyama

2

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6 February 2018

Keisuke Kuida

3

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6 February 2018

Hiroshi Mori

4

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6 February 2018

publication date

1 March 2004

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6 February 2018

Journal of Neuropathology & Experimental Neurology

published in

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6 February 2018

volume

63

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6 February 2018

issue

3

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6 February 2018

page(s)

255-261

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6 February 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Effects of injected Alzheimer beta-amyloid cores in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Expression of ced-3 and ced-9 homologs in Alzheimer's disease cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Sealing one's fate: control of cell death in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Caspases as treatment targets in stroke and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

A short cytoplasmic domain of the amyloid precursor protein induces apoptosis in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

A suicide note from Alzheimer disease neurons?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Microglia as a source and target of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Amyloid beta protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Presence of double-strand breaks with single-base 3' overhangs in cells undergoing apoptosis but not necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

Morphologic and biochemical hallmarks of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.3.255

21 January 2018

Identifiers

DOI

10.1093/JNEN/63.3.255

1 reference

6 February 2018

PubMed ID

15055449

1 reference

6 February 2018