Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide (Q34963822)

5 August 2017

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title

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide (English)

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5 August 2017

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Joseph Rogers

1

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5 August 2017

Ron Strohmeyer

series ordinal

2

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5 August 2017

C J Kovelowski

series ordinal

3

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5 August 2017

Rena Li

series ordinal

4

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5 August 2017

1 November 2002

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5 August 2017

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5 August 2017

40

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5 August 2017

260-269

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5 August 2017

2

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Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein.

5 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Inflammation and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

A protein with characteristics of factor H is present on rodent platelets and functions as the immune adherence receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Transcriptional regulation of inflammatory secreted phospholipases A(2).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Nuclear translocation of NF-kappaB in cholinergic neurons of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The beta A4 amyloid protein precursor in human circulation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Synthesis and secretion of complement proteins by macrophages

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immune adherence by the fourth component of complement

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Activation of the complement system.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement effector mechanisms in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Lysis of RNA tumor viruses by human serum: direct antibody-independent triggering of the classical complement pathway

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement activation by cross-linked truncated and chimeric full-length beta-amyloid

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Pro-inflammatory complement activation by the A beta peptide of Alzheimer's disease is biologically significant and can be blocked by vaccinia virus complement control protein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immune adherence and the processing of soluble complement-fixing antibody/DNA immune complexes in mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The role of complement in Alzheimer's disease pathology

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Amyloid deposition is associated with c-Jun expression in Alzheimer's disease and amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Identification of murine complement receptor type 2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus. A light and electron microscopical study

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochemical study using a novel monoclonal antibody

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement gene expression in mouse microglia and astrocytes in culture: comparisons with mouse peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Deficiency of complement component C3 is associated with accelerated removal of soluble 123I-labelled aggregates of IgG from the circulation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The Clearance of Immune Complexes From the Circulation of Man and Other Primates

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Autoantibodies to amyloid-beta and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Morphogenesis of amyloid plaques in 87V murine scrapie

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Changes of p53 in the brains of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Alteration of transcription factors NF-kappaB and STAT1 in Alzheimer's disease brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Alzheimer's beta-amyloid peptide 1-42 induces a phagocytic response in murine microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Phagocytosis is regulated by nitric oxide in murine microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Estrogen enhances uptake of amyloid beta-protein by microglia derived from the human cortex

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immune system associated antigens expressed by cells of the human central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Expression of Fos, Jun, and Krox family proteins in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Possible different mechanism between amyloid-beta (25-35)-and substance P-induced chemotaxis of murine microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Quantitative neuronal c-fos and c-jun expression in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Activation of the classical complement pathway in brain tissue of Alzheimer patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Priming of monocyte respiratory burst by beta-amyloid fragment (25-35)

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35].

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

PKC and tyrosine kinase involvement in amyloid beta (25-35)-induced chemotaxis of microglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Reactive microglia in aging and dementia: an immunohistochemical study of postmortem human brain tissue.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement C1qB and C4 mRNAs responses to lesioning in rat brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

MHC class II-positive microglia in human brain: association with Alzheimer lesions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement-mediated solubilization of immune complexes and their interaction with complement C3 receptors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement activation by beta-amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Elucidating molecular mechanisms of Alzheimer's disease in microglial cultures

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Microglial activation in early stages of amyloid beta protein deposition.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

beta-peptide immunization: a possible new treatment for Alzheimer disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Physiological and pathological aspects of circulating immune complexes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

3D-Reconstruction of microglia and amyloid in APP23 transgenic mice: no evidence of intracellular amyloid

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Enhancement of immunoreactivity for NF-kappa B in the hippocampal formation and cerebral cortex of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Apoptosis of cultured microglia by the deprivation of macrophage colony-stimulating factor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement gene expression in human brain: comparison between normal and Alzheimer disease cases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement depletion accelerates the clearance of immune complexes from the circulation of primates

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Differential binding of immunoglobulin A and immunoglobulin G1 immune complexes to primate erythrocytes in vivo. Immunoglobulin A immune complexes bind less well to erythrocytes and are preferentially deposited in glomeruli

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Multivalent binding of complement protein C1Q to the amyloid beta-peptide (A beta) promotes the nucleation phase of A beta aggregation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Aggregation state-dependent activation of the classical complement pathway by the amyloid beta peptide.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Complement component C1q modulates the phagocytosis of Abeta by microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Expression of activating transcription factor-2 (ATF-2), one of the cyclic AMP response element (CRE) binding proteins, in Alzheimer disease and non-neurological brain tissues.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Chemotaxis by a CNS macrophage, the microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

The role of A beta 42 in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10153

7 January 2021

Identifiers

DOI

10.1002/GLIA.10153

1 reference

5 August 2017

1 reference