Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins (Q29547593)

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23 April 2017

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Lambert MP

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Barlow AK

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Chromy BA

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Edwards C

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Freed R

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Liosatos M

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Morgan TE

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Rozovsky I

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Trommer B

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Wals P

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Zhang C

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Finch CE

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Krafft GA

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Klein WL

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language of work or name

1 reference

23 April 2017

publication date

26 May 1998

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

23 April 2017

published in

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volume

95

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23 April 2017

page(s)

6448-53

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issue

11

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Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene

23 April 2017

cites work

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

23 April 2017

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

23 April 2017

1 reference

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RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

23 April 2017

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

23 April 2017

1 reference

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

23 April 2017

1 reference

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

23 April 2017

1 reference

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Integrins and signal transduction pathways: the road taken

23 April 2017

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

23 April 2017

1 reference

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

23 April 2017

1 reference

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Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

23 April 2017

1 reference

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

23 April 2017

1 reference

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A simple method for organotypic cultures of nervous tissue

23 April 2017

1 reference

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Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

23 April 2017

1 reference

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Rapid impact of beta-amyloid on paxillin in a neural cell line

3 June 2018

1 reference

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CNS neuronal focal adhesion kinase forms clusters that co-localize with vinculin.

3 June 2018

1 reference

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A beta peptide enhances focal adhesion kinase/Fyn association in a rat CNS nerve cell line

3 June 2018

1 reference

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Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity

3 June 2018

1 reference

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Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

3 June 2018

1 reference

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Apolipoprotein J and Alzheimer's amyloid beta solubility

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27787

Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein

3 June 2018

1 reference

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Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

3 June 2018

1 reference

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Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

3 June 2018

1 reference

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

3 June 2018

1 reference

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Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

3 June 2018

1 reference

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The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

3 June 2018

1 reference

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7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracel

3 June 2018

1 reference

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Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

3 June 2018

1 reference

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

3 June 2018

1 reference

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Oncogenic activation of p59fyn tyrosine protein kinase by mutation of its carboxyl-terminal site of tyrosine phosphorylation, tyrosine 528.

3 June 2018

1 reference

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

3 June 2018

1 reference

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Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

3 June 2018

1 reference

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Role of the beta-amyloid protein in Alzheimer's disease.

3 June 2018

1 reference

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Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths

3 June 2018

1 reference

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3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27787

Chaperoning Alzheimer's amyloids

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27787

Src family protein tyrosine kinases and cellular signal transduction pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27787

Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide

3 June 2018

1 reference

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Beta/A4-evoked degeneration of differentiated SH-SY5Y human neuroblastoma cells

3 June 2018

1 reference

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Clonal cell lines from the rat central nervous system.

3 June 2018

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New perspectives on Alzheimer's disease

3 June 2018

1 reference

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Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin.

3 June 2018

1 reference

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

3 June 2018

1 reference

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat.

3 June 2018

1 reference

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Glutamate Neurotoxicity and the Inhibition of Protein Synthesis in the Hippocampal Slice

3 June 2018

1 reference

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Alzheimer's debate boils over

3 June 2018

1 reference

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

3 June 2018

1 reference

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Distribution of clusterin in Alzheimer brain tissue

3 June 2018

1 reference

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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

3 June 2018

1 reference

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Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

3 June 2018

1 reference

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Soluble multimeric Alzheimer beta(1-40) pre-amyloid complexes in dilute solution.

26 November 2018

1 reference

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Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

26 November 2018

1 reference

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The protein tyrosine kinase, fyn, in Alzheimer's disease pathology.

26 November 2018

1 reference

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Purification and characterization of brain clusterin

26 November 2018

1 reference

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Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

26 November 2018

1 reference

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The induction of multiple cell cycle events precedes target-related neuronal death.

26 November 2018

1 reference

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Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress.

26 November 2018

1 reference

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26 November 2018

1 reference

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Development of kainic acid and N-methyl-D-aspartic acid toxicity in organotypic hippocampal cultures.

26 November 2018

1 reference

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Binding of heparan sulfate glycosaminoglycan to beta-amyloid peptide: inhibition by potentially therapeutic polysulfated compounds

26 November 2018

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12 December 2020

Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide

1 reference

12 December 2020

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

12 December 2020

Beta-amyloid deposition and paired helical filament formation: which histopathological feature is more significant in Alzheimer's disease?

1 reference

12 December 2020

AP5 blocks LTP in developing rat dentate gyrus and unmasks LTD

1 reference

12 December 2020

fyn tyrosine kinase is involved in keratinocyte differentiation control

1 reference

12 December 2020

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

1 reference

12 December 2020

The nanometer-scale structure of amyloid-beta visualized by atomic force microscopy

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12 December 2020

Identifiers

DOI

10.1073/PNAS.95.11.6448

1 reference

131277

ADS bibcode

1998PNAS...95.6448L

0 references

131277

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9600986

2 references

23 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9600986

2 references

23 April 2017