Recognition of the pre-miRNA structure by Drosophila Dicer-1. (Q47070637)

5 January 2018

title

Recognition of the pre-miRNA structure by Drosophila Dicer-1. (English)

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5 January 2018

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GOA release 2020-03-11

author

Yukihide Tomari

5

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author name string

Akihisa Tsutsumi

1

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5 January 2018

Tomoko Kawamata

2

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5 January 2018

Natsuko Izumi

3

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5 January 2018

Hervé Seitz

4

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publication date

18 September 2011

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5 January 2018

Nature Structural & Molecular Biology

published in

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volume

18

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issue

10

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page(s)

1153-1158

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https://scigraph.springernature.com/pub.10.1038/nsmb.2125

exact match

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cites work

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

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Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

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The role of PACT in the RNA silencing pathway

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Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

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Argonaute2, a link between genetic and biochemical analyses of RNAi

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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes

21 January 2018

1 reference

In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90.

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Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

21 January 2018

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ATP-dependent human RISC assembly pathways

21 January 2018

1 reference

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

1 reference

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

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RISC assembly defects in the Drosophila RNAi mutant armitage.

21 January 2018

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

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Slicer function of Drosophila Argonautes and its involvement in RISC formation

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

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Ribonuclease activity and RNA binding of recombinant human Dicer

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

21 January 2018

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Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease

21 January 2018

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Functional anatomy of the Drosophila microRNA-generating enzyme

21 January 2018

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

21 January 2018

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Structural basis for double-stranded RNA processing by Dicer

21 January 2018

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SF1 and SF2 helicases: family matters

21 January 2018

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RNA helicases at work: binding and rearranging

21 January 2018

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Dead-box proteins: a family affair--active and passive players in RNP-remodeling

21 January 2018

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The mechanism of ATP-dependent RNA unwinding by DEAD box proteins

21 January 2018

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Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode

21 January 2018

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Structural insights into RNA processing by the human RISC-loading complex

21 January 2018

1 reference

Structure of the human Dicer-TRBP complex by electron microscopy

21 January 2018

1 reference

ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

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Dicer's helicase domain is required for accumulation of some, but not all, C. elegans endogenous siRNAs.

21 January 2018

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Identification of microRNA processing determinants by random mutagenesis of Arabidopsis MIR172a precursor.

21 January 2018

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RNA secondary structural determinants of miRNA precursor processing in Arabidopsis.

21 January 2018

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Structure determinants for accurate processing of miR172a in Arabidopsis thaliana.

21 January 2018

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A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159.

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The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1.

21 January 2018

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Autoinhibition of human dicer by its internal helicase domain

21 January 2018

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A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

21 January 2018

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Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

21 January 2018

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Sorting of Drosophila small silencing RNAs

21 January 2018

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Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

21 January 2018

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Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression.

21 January 2018

1 reference

A direct role for Hsp90 in pre-RISC formation in Drosophila.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21926993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2125

1 reference

5 January 2018

PubMed ID

21926993

1 reference

5 January 2018