Raf and akt mediate distinct aspects of sensory axon growth (Q45345797)

13 December 2017

Raf and akt mediate distinct aspects of sensory axon growth (English)

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13 December 2017

Annette Markus

1

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13 December 2017

Jian Zhong

series ordinal

2

1 reference

13 December 2017

William D Snider

series ordinal

3

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13 December 2017

language of work or name

English

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publication date

1 July 2002

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13 December 2017

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13 December 2017

35

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13 December 2017

65-76

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13 December 2017

1

1 reference

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

13 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Bcl-2 promotes regeneration of severed axons in mammalian CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Slow axonal transport models come full circle: evidence that microtubule sliding mediates axon elongation and tubulin transport

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Akt participation in the Wnt signaling pathway through Dishevelled

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Regulation of axonal caliber, neurofilament content, and nuclear localization in mature sensory neurons by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

PC12 cell mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Bcl-2 influences axonal growth rate in embryonic sensory neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

MEK kinase activity is not necessary for Raf-1 function

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neurotrophin signal transduction in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Glial cell line-derived neurotrophic factor administration in postnatal life results in motor unit enlargement and continuous synaptic remodeling at the neuromuscular junction.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Nerve growth factor-stimulated mitogen-activated protein kinase activity is not necessary for neurite outgrowth of chick dorsal root ganglion sensory and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neuronal intermediate filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neurotrophins support the development of diverse sensory axon morphologies.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Different signaling pathways mediate regenerative versus developmental sensory axon growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

NGF-mediated survival depends on p21ras in chick sympathetic neurons from the superior cervical but not from lumbosacral ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Effects of GDNF on axotomized sensory and motor neurons in adult rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Adult mammalian sensory and motor neurons: roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Development of sensory neurons in the absence of NGF/TrkA signaling in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Genetic control of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The Akt proto-oncogene links Ras to Pak and cell survival signals

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

A versatile microporation technique for the transfection of cultured CNS neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Neurotrophins are required for nerve growth during development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Differential effects of NGF and NT-3 on embryonic trigeminal axon growth patterns

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Introduction of a neurotrophin-3 transgene into muscle selectively rescues proprioceptive neurons in mice lacking endogenous neurotrophin-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900752-3

7 January 2021

10.1016/S0896-6273(02)00752-3

Identifiers

DOI

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13 December 2017

1 reference