p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons (Q28587133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9852579%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9852579%20AND%20SRC:MED&resulttype=core&format=json

V-raf-leukemia viral oncogene 1

7 December 2019

main subject

1 reference

GOA release 2020-03-11

author name string

L J Klesse

series ordinal

1

1 reference

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7 December 2019

L F Parada

series ordinal

2

1 reference

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7 December 2019

language of work or name

English

0 references

publication date

1 December 1998

1 reference

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7 December 2019

published in

Journal of Neuroscience

2 references

31 January 2017

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7 December 2019

volume

18

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31 January 2017

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7 December 2019

page(s)

10420-10428

1 reference

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7 December 2019

issue

24

2 references

31 January 2017

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

7 December 2019

cites work

1 reference

12 December 2020

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

1 reference

12 December 2020

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

12 December 2020

Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival

1 reference

12 December 2020

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

12 December 2020

Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells

1 reference

12 December 2020

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

12 December 2020

Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal

1 reference

12 December 2020

Neurotrophin signal transduction by the Trk receptor

1 reference

12 December 2020

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons

1 reference

12 December 2020

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

12 December 2020

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

1 reference

12 December 2020

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

1 reference

12 December 2020

Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons

1 reference

12 December 2020

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

1 reference

12 December 2020

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

12 December 2020

Intracellular signaling pathways activated by neurotrophic factors

1 reference

12 December 2020

Neurotrophin regulation of the developing nervous system: analyses of knockout mice

1 reference

12 December 2020

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

12 December 2020

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

1 reference

12 December 2020

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1 reference

12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

12 December 2020

Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP

1 reference

12 December 2020

Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism

1 reference

12 December 2020

Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

12 December 2020

Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

1 reference

12 December 2020

Signal transduction by the neurotrophin receptors

1 reference

12 December 2020

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

12 December 2020

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

12 December 2020

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

12 December 2020

Regulators of cell death

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12 December 2020

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

1 reference

12 December 2020

Mechanism of activation of a human oncogene

1 reference

12 December 2020

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation

1 reference

12 December 2020

Ras p21 protein promotes survival and differentiation of human embryonic neural crest-derived cells

1 reference

12 December 2020

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

1 reference

12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

12 December 2020

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1 reference

12 December 2020

Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones

1 reference

12 December 2020

Neurofibromatosis type 1 and Ras-mediated signaling: filling in the GAPs.

1 reference

12 December 2020

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

12 December 2020

Neuronal precursor cells in chick dorsal root ganglia: differentiation and survival in vitro.

1 reference

12 December 2020

p75NTR and apoptosis: Trk-dependent and Trk-independent effects

1 reference

12 December 2020

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

12 December 2020

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

12 December 2020

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

12 December 2020

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1 reference

12 December 2020

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

12 December 2020

Mutational activation of c-raf-1 and definition of the minimal transforming sequence

1 reference

12 December 2020

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

12 December 2020

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

12 December 2020

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

1 reference

12 December 2020

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

12 December 2020

Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

1 reference

12 December 2020

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death

1 reference

12 December 2020

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

12 December 2020

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

12 December 2020

Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase

1 reference

12 December 2020

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

12 December 2020

Dorsal root ganglion neurons require functional neurotrophin receptors for survival during development

1 reference

12 December 2020

10.1523/JNEUROSCI.18-24-10420.1998

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9852579%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9852579%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

2 references

31 January 2017