Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis (Q45267238)

11 December 2017

Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis (English)

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11 December 2017

Jie Han

1

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11 December 2017

Leslie A Goldstein

2

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11 December 2017

Brian R Gastman

3

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11 December 2017

Asaf Rabinovitz

4

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11 December 2017

Hannah Rabinowich

5

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11 December 2017

language of work or name

English

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publication date

15 February 2005

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Journal of Biological Chemistry

11 December 2017

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11 December 2017

280

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11 December 2017

16

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11 December 2017

16383-16392

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MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

11 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Up-regulated expression of murine Mcl1/EAT, a bcl-2 related gene, in the early stage of differentiation of murine embryonal carcinoma cells and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Role of Bcl-2 family members in immunity and disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Mechanisms involved in interleukin-15-induced suppression of human neutrophil apoptosis: role of the anti-apoptotic Mcl-1 protein and several kinases including Janus kinase-2, p38 mitogen-activated protein kinase and extracellular signal-regulated k

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Fas-triggered phosphatidylserine exposure is modulated by intracellular ATP.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B-mediated apoptosis--the elephant and the blind men?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Transcriptional and translational control of Mcl-1 during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411377200

Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Granzyme B: a natural born killer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

Bcl-2, via Its BH4 Domain, Blocks Apoptotic Signaling Mediated by Mitochondrial Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411377200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411377200

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11 December 2017

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