Granzyme B: a natural born killer (Q35129699)

6 August 2017

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title

Granzyme B: a natural born killer (English)

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6 August 2017

2

Ray V Rajotte

1 reference

6 August 2017

Sarah J Lord

1

1 reference

PubMed ID

12752668

6 August 2017

Gregory S Korbutt

series ordinal

3

1 reference

PubMed ID

12752668

6 August 2017

R Chris Bleackley

series ordinal

4

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6 August 2017

1 June 2003

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6 August 2017

Immunological Reviews

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6 August 2017

193

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6 August 2017

31-38

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Lymphocyte-mediated cytotoxicity.

6 August 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Functional significance of the perforin/granzyme cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

ICE-like proteases in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Enzymatic control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

Cytotoxic T lymphocytes: all roads lead to death

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Conversion of the substrate specificity of mouse proteinase granzyme B.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Interactions of recombinant and platelet transforming growth factor-beta 1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00044.X

7 January 2021

10.1034/J.1600-065X.2003.00044.X

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12752668