Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer. (Q43144913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383402%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer (English)

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23 February 2020

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2

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23 February 2020

author name string

Michael J Wagner

series ordinal

1

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23 February 2020

publication date

4 February 2013

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23 February 2020

published in

Frontiers in Oncology

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23 February 2020

volume

3

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23 February 2020

page(s)

9

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Medulloblastomics: the end of the beginning

23 February 2020

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody

25 May 2018

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25 May 2018

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Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

25 May 2018

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25 May 2018

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Insulin-like growth factor-I receptor expression regulates neuroblastoma metastasis to bone.

25 May 2018

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Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor.

25 May 2018

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IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1

25 May 2018

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25 May 2018

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EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Antibody to type I insulinlike growth factor receptor inhibits growth of Wilms' tumor in culture and in athymic mice

25 May 2018

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Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II.

25 May 2018

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Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor

25 May 2018

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Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas

25 May 2018

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Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib.

15 August 2018

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Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

15 August 2018

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Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.

15 August 2018

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Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.

15 August 2018

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Insulin-like growth factor I receptor activity in human medulloblastomas.

15 August 2018

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Insulin-like growth factor (IGF) binding protein-3 inhibits type 1 IGF receptor activation independently of its IGF binding affinity

15 August 2018

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Recent advances in neuroblastoma

15 August 2018

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Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice

29 September 2018

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Human osteosarcoma cell lines are dependent on insulin-like growth factor I for in vitro growth

3 November 2018

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12 December 2020

Proteolysis of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in 150-kilodalton IGFBP complexes by a cation-dependent protease activity in adult rat serum promotes the release of bound IGF-I

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12 December 2020

Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype

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12 December 2020

Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumors

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12 December 2020

Transcriptional regulation of IGF-I receptor gene expression by the PAX3-FKHR oncoprotein

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12 December 2020

Identifiers

DOI

10.3389/FONC.2013.00009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383402%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383402%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383402%20AND%20SRC:MED&resulttype=core&format=json