Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program. (Q34414710)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20166202%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program (English)

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18 January 2020

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3

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18 January 2020

C P Reynolds

6

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18 January 2020

Min H Kang

7

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18 January 2020

1

Peter J Houghton

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18 January 2020

8

John M Maris

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18 January 2020

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Malcolm A Smith

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18 January 2020

4

E Anders Kolb

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18 January 2020

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Stephen T Keir

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18 January 2020

author name string

Christopher L Morton

2

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18 January 2020

Jianrong Wu

9

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18 January 2020

publication date

1 July 2010

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18 January 2020

published in

Pediatric Blood Cancer

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18 January 2020

volume

54

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18 January 2020

page(s)

921-926

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18 January 2020

issue

7

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Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003867

IMC-A12, a human IgG1 monoclonal antibody to the insulin-like growth factor I receptor

6 July 2018

1 reference

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Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.

6 July 2018

1 reference

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A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations

6 July 2018

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Disrupting insulin-like growth factor signaling as a potential cancer therapy

6 July 2018

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Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer

6 July 2018

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IGF-IR: potential role in antitumor agents.

6 July 2018

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IGF-I mediated survival pathways in normal and malignant cells

6 July 2018

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Evaluation of the antitumor efficacy, pharmacokinetics, and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo

6 July 2018

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In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative, against pediatric cancer models

6 July 2018

1 reference

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Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody

6 July 2018

1 reference

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Structure and function of the insulin-like growth factor I receptor

6 July 2018

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Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors

6 July 2018

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Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

6 July 2018

1 reference

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

6 July 2018

1 reference

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Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents

6 July 2018

1 reference

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The pediatric preclinical testing program: description of models and early testing results.

28 July 2018

1 reference

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Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

27 October 2018

1 reference

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Inhibition of proliferation in human MNNG/HOS osteosarcoma and SK-ES-1 Ewing sarcoma cell lines in vitro and in vivo by antagonists of growth hormone-releasing hormone: effects on insulin-like growth factor II

27 October 2018

1 reference

12 December 2020

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors

1 reference

12 December 2020

Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells

1 reference

12 December 2020

In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2

1 reference

12 December 2020

Insulin-like growth factors and cancer

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12 December 2020

Identifiers

DOI

10.1002/PBC.22367

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20166202%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20166202%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

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