Structural Basis for G Protein-Coupled Receptor Activation (Q42694413)

28967738

5 November 2017

title

Structural Basis for G Protein-Coupled Receptor Activation (English)

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28967738

G protein-coupled receptor

5 November 2017

main subject

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author

Andrew C Kruse

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

author name string

Aashish Manglik

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

2 October 2017

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5 November 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

volume

56

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

issue

42

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

page(s)

5628-5634

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

15 May 2020

cites work

1 reference

12 December 2020

Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus

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TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor

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12 December 2020

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

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Crystal structure of opsin in its G-protein-interacting conformation

1 reference

12 December 2020

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

1 reference

12 December 2020

Highly conserved tyrosine stabilizes the active state of rhodopsin

1 reference

12 December 2020

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

1 reference

12 December 2020

Structure and function of an irreversible agonist-β(2) adrenoceptor complex

1 reference

12 December 2020

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

1 reference

12 December 2020

Structure of an agonist-bound human A2A adenosine receptor

1 reference

12 December 2020

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

1 reference

12 December 2020

Crystal structure of the β2 adrenergic receptor-Gs protein complex

1 reference

12 December 2020

Pathway and mechanism of drug binding to G-protein-coupled receptors.

1 reference

12 December 2020

Activation mechanism of the β2-adrenergic receptor

1 reference

12 December 2020

Micro-crystallography comes of age.

1 reference

12 December 2020

The dynamic process of β(2)-adrenergic receptor activation

1 reference

12 December 2020

Structural Basis for Molecular Recognition at Serotonin Receptors

1 reference

12 December 2020

Structural Features for Functional Selectivity at Serotonin Receptors

1 reference

12 December 2020

Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective

1 reference

12 December 2020

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

1 reference

12 December 2020

Activation and allosteric modulation of a muscarinic acetylcholine receptor

1 reference

12 December 2020

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

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Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli

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Allosteric sodium in class A GPCR signaling

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Agonist-bound structure of the human P2Y12 receptor

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Calcium-sensing receptor 20 years later

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12 December 2020

Biased ligands at G-protein-coupled receptors: promise and progress

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High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875

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12 December 2020

A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes.

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12 December 2020

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

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12 December 2020

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

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12 December 2020

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

1 reference

12 December 2020

Structural prerequisites for G-protein activation by the neurotensin receptor

1 reference

12 December 2020

Structural insights into µ-opioid receptor activation

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12 December 2020

How Can Mutations Thermostabilize G-Protein-Coupled Receptors?

1 reference

12 December 2020

Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor

1 reference

12 December 2020

Olfactory receptor signaling.

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Activation of the A2A adenosine G-protein-coupled receptor by conformational selection

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12 December 2020

Structure of the adenosine A(2A) receptor bound to an engineered G protein.

1 reference

12 December 2020

Activation mechanism of endothelin ETB receptor by endothelin-1

1 reference

12 December 2020

GPCR Dynamics: Structures in Motion

1 reference

12 December 2020

Nanobodies to Study G Protein-Coupled Receptor Structure and Function

1 reference

12 December 2020

Crystal Structure of an LSD-Bound Human Serotonin Receptor

1 reference

12 December 2020

Phase-plate cryo-EM structure of a class B GPCR-G-protein complex

1 reference

12 December 2020

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells.

1 reference

12 December 2020

Structural Basis for Apelin Control of the Human Apelin Receptor

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Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

1 reference

12 December 2020

Crystal structure of the GLP-1 receptor bound to a peptide agonist.

1 reference

12 December 2020

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

1 reference

12 December 2020

A Bright Future for Serial Femtosecond Crystallography with XFELs.

1 reference

12 December 2020

How Ligands Illuminate GPCR Molecular Pharmacology

1 reference

12 December 2020

Opiate agonists and antagonists discriminated by receptor binding in brain.

1 reference

12 December 2020

10.1021/ACS.BIOCHEM.7B00747

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6613644&resulttype=core&format=json

15 May 2020

28967738

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