Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling (Q41493003)

1 October 2017

Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling (English)

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1 October 2017

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15

Richard G Pestell

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1 October 2017

2

Chenguang Wang

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1 October 2017

6

Andrew A Quong

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1 October 2017

3

Xuanmao Jiao

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1 October 2017

Zhiping Li

1

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1 October 2017

Yinan Lu

4

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1 October 2017

Maofu Fu

5

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1 October 2017

Chip Dye

7

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1 October 2017

Jianguo Yang

8

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1 October 2017

Maozheng Dai

9

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1 October 2017

Xiaoming Ju

10

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1 October 2017

Xueping Zhang

11

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1 October 2017

Anping Li

12

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1 October 2017

Peter Burbelo

13

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1 October 2017

E Richard Stanley

14

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1 October 2017

language of work or name

English

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publication date

1 June 2006

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1 October 2017

17

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Molecular and Cellular Biology

inferred from page(s)

published in

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1 October 2017

26

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1 October 2017

4240-4256

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1 October 2017

11

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describes a project that uses

1 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1489104/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/1489104

inferred from PubMed Central ID database lookup

cites work

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Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment

11 June 2018

1 reference

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SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

11 June 2018

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G1 cell-cycle control and cancer

11 June 2018

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Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting

11 June 2018

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Minireview: Cyclin D1: normal and abnormal functions

11 June 2018

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Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

11 June 2018

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Biologically meaningful expression profiling across species using heterologous hybridization to a cDNA microarray

11 June 2018

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B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts

11 June 2018

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Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential

11 June 2018

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Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition

11 June 2018

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

11 June 2018

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Altered Rho GTPase signaling pathways in breast cancer cells.

11 June 2018

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Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.

11 June 2018

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Rho and Rac take center stage

11 June 2018

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Cytoplasmic p21Cip1 Is Involved in Ras-induced Inhibition of the ROCK/LIMK/Cofilin Pathway

11 June 2018

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Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation

11 June 2018

1 reference

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Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

11 June 2018

1 reference

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Cyclin D1 governs adhesion and motility of macrophages

11 June 2018

1 reference

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Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration

11 June 2018

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Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis

11 June 2018

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IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

11 June 2018

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Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1

11 June 2018

1 reference

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

11 June 2018

1 reference

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Ratio statistics of gene expression levels and applications to microarray data analysis

11 June 2018

1 reference

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Myosin X is a downstream effector of PI(3)K during phagocytosis

11 June 2018

1 reference

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Timing of cyclin D1 expression within G1 phase is controlled by Rho.

11 June 2018

1 reference

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Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

11 June 2018

1 reference

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Specific protection against breast cancers by cyclin D1 ablation

11 June 2018

1 reference

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PTEN controls tumor-induced angiogenesis

11 June 2018

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Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases

11 June 2018

1 reference

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Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

11 June 2018

1 reference

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Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

11 June 2018

1 reference

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Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice

11 June 2018

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Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts

11 June 2018

1 reference

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Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

11 June 2018

1 reference

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Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

CDK inhibitors: positive and negative regulators of G1-phase progression

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Rho GTPases control polarity, protrusion, and adhesion during cell movement

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Angiotensin II activation of cyclin D1-dependent kinase activity

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

A novel cyclin encoded by a bcl1-linked candidate oncogene

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Actin' up: RhoB in cancer and apoptosis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489104

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

30 September 2018

1 reference

12 December 2020

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

1 reference

12 December 2020

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

12 December 2020

Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

1 reference

12 December 2020

Role of the Fos family members, c-Fos, Fra-1 and Fra-2, in the regulation of cell motility

1 reference

12 December 2020

Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice

1 reference

12 December 2020

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

12 December 2020

Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts

1 reference

12 December 2020

Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone

1 reference

12 December 2020

PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.02124-05

1 reference

1 October 2017

1 reference

1 October 2017

1 reference