G1 cell-cycle control and cancer (Q34368858)

1 August 2017

title

G1 cell-cycle control and cancer (English)

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1 August 2017

Joan Massagué

1

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1 August 2017

publication date

1 November 2004

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1 August 2017

language of work or name

0 references

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1 August 2017

volume

432

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1 August 2017

issue

7015

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1 August 2017

page(s)

298-306

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publication type of scholarly work

1 August 2017

review article

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Cyclin-dependent kinases: engines, clocks, and microprocessors

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Recycling the Cell Cycle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Regulation of chromosome replication

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Dynamics of pre-replication complex proteins during the cell division cycle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cyclin E ablation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Signaling networks that link cell proliferation and cell fate

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

A revised picture of the E2F transcriptional network and RB function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The retinoblastoma gene family in differentiation and development.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Principles of tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mouse development and cell proliferation in the absence of D-cyclins.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

p27 as a target for cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover

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https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Un ménage à quatre: the molecular biology of chromosome segregation in meiosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Targeting RAS signalling pathways in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

RAS and RHO GTPases in G1-phase cell-cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase Signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The discovery of receptor tyrosine kinases: targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Opportunities and challenges in the development of kinase inhibitor therapy for cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Protein kinase inhibitors: insights into drug design from structure.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Malignant glioma: genetics and biology of a grave matter.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cell death: critical control points

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Death Receptors: Signaling and Modulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cytochrome C-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Radiation and ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The TOR pathway: a target for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The LKB1 tumor suppressor negatively regulates mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Signaling control of mRNA translation in cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The renaissance of GSK3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The glamour and gloom of glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The Myc/Max/Mad network and the transcriptional control of cell behavior

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Transcriptional repression by Myc.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

c-MYC: more than just a matter of life and death

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The two faces of transforming growth factor beta in carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The p53 and Mdm2 families in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

p63 and p73 are not required for the development and p53-dependent apoptosis of T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Mammalian SIRT1 represses forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

FoxO: linking new signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Id proteins in development, cell cycle and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Contribution of stem cells and differentiated cells to epidermal tumours

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Prospective identification of tumorigenic breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

The Hedgehog response network: sensors, switches, and routers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Genetic and epigenetic alterations in colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Overriding imatinib resistance with a novel ABL kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03094

7 January 2021

Identifiers

DOI

10.1038/NATURE03094

1 reference

release_so4jbisscrcyxbqlak36yxa7nu

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/so4jbisscrcyxbqlak36yxa7nu

24 November 2022

mapped directly with Wikidata item

1 reference