Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice (Q28510765)

GOA release 2020-03-11

Cyclin D1

1 reference

Catenin (cadherin associated protein), beta 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1 reference

12

Richard G. Pestell

1 reference

25 January 2017

6

Dolores Di Vizio

1 reference

25 January 2017

James Hulit

1

1 reference

25 January 2017

Chenguang Wang

2

1 reference

25 January 2017

Zhiping Li

3

1 reference

25 January 2017

Chris Albanese

4

1 reference

25 January 2017

Mahadev Rao

5

1 reference

25 January 2017

Salimuddin Shah

7

1 reference

25 January 2017

Stephen W. Byers

8

1 reference

25 January 2017

Radma Mahmood

9

1 reference

25 January 2017

Leonard H. Augenlicht

10

1 reference

25 January 2017

Robert Russell

Molecular and Cellular Biology

11

1 reference

25 January 2017

language of work or name

English

0 references

publication date

1 September 2004

1 reference

25 January 2017

1 reference

25 January 2017

24

1 reference

25 January 2017

17

1 reference

25 January 2017

7598–7611

1 reference

25 January 2017

describes a project that uses

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC507010/fullTextXML

inferred from PubMed Central ID database lookup

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Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

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APC-dependent suppression of colon carcinogenesis by PPARgamma

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

19 March 2017

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

19 March 2017

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

19 March 2017

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

19 March 2017

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

19 March 2017

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Induction of cyclin D1 by simian virus 40 small tumor antigen

19 March 2017

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Functional interaction of beta-catenin with the transcription factor LEF-1

19 March 2017

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

19 March 2017

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

19 March 2017

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Association of the APC tumor suppressor protein with catenins

19 March 2017

1 reference

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Association of the APC gene product with beta-catenin

19 March 2017

1 reference

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From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

19 March 2017

1 reference

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beta-catenin is a target for the ubiquitin-proteasome pathway

19 March 2017

1 reference

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Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

7 April 2017

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

7 April 2017

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

7 April 2017

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

7 April 2017

1 reference

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

7 April 2017

1 reference

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Linking colorectal cancer to Wnt signaling

7 April 2017

1 reference

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

7 April 2017

1 reference

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Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia

7 April 2017

1 reference

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A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

29 September 2017

1 reference

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Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter

29 September 2017

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Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

29 September 2017

1 reference

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A gene expression profile that defines colon cell maturation in vitro.

29 September 2017

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The role of cadherin, beta-catenin, and AP-1 in retinoid-regulated carcinoma cell differentiation and proliferation

29 September 2017

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ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells

29 September 2017

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PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

29 September 2017

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Specific protection against breast cancers by cyclin D1 ablation

29 September 2017

1 reference

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Re-SET-ting heterochromatin by histone methyltransferases

29 September 2017

1 reference

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Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Immunodetectable cyclin D(1)is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Regulation of beta-catenin levels and localization by overexpression of plakoglobin and inhibition of the ubiquitin-proteasome system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Cadherins and catenins in development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breast.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Aberrant crypts: putative preneoplastic foci in human colonic mucosa.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonic mucosa.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507010

Emergence of adenomatous aberrant crypt foci (ACF) from hyperplastic ACF with concomitant increase in cell proliferation

27 November 2018

1 reference

12 December 2020

PML is a target gene of beta-catenin and plakoglobin, and coactivates beta-catenin-mediated transcription

1 reference

12 December 2020

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

1 reference

12 December 2020

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1 reference

12 December 2020

Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells

1 reference

12 December 2020

Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer

1 reference

12 December 2020

Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture

1 reference

12 December 2020

Prognostic impact of p21/waf1/cip1 in colorectal cancer

1 reference

12 December 2020

Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal

1 reference

12 December 2020

The identification of monoclonality in human aberrant crypt foci

1 reference

12 December 2020

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

1 reference

12 December 2020

The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas

1 reference

12 December 2020