Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. (Q40594671)

21 September 2017

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

Membrane metalloendopeptidase

12 May 2020

main subject

1 reference

GOA release 2020-03-11

author

Shin-ichi Muramatsu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

author name string

Nobuhisa Iwata

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Hiroaki Mizukami

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Keiro Shirotani

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Yoshie Takaki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Bao Lu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Norma P Gerard

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Craig Gerard

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Keiya Ozawa

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

Takaomi C Saido

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 January 2004

1 reference

21 September 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

volume

24

1 reference

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12 May 2020

page(s)

991-998

1 reference

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12 May 2020

issue

4

1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

12 May 2020

cites work

1 reference

12 December 2020

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

1 reference

12 December 2020

Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.

1 reference

12 December 2020

Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide.

1 reference

12 December 2020

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

1 reference

12 December 2020

Inflammation and Alzheimer disease: the good, the bad, and the ugly.

1 reference

12 December 2020

Metabolic regulation of brain Abeta by neprilysin.

1 reference

12 December 2020

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

1 reference

12 December 2020

Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

1 reference

12 December 2020

Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons.

1 reference

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?

1 reference

12 December 2020

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

Adeno-associated virus vectors for gene transfer to the brain.

1 reference

12 December 2020

Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.

1 reference

12 December 2020

Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.

1 reference

12 December 2020

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

1 reference

12 December 2020

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

12 December 2020

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

1 reference

12 December 2020

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

1 reference

12 December 2020

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

1 reference

12 December 2020

Alzheimer's disease, neuropeptides, neuropeptidase, and amyloid-beta peptide metabolism

1 reference

12 December 2020

Membrane Localization of Endopeptidase‐24.11 and Peptidyl Dipeptidase A (Angiotensin Converting Enzyme) in the Pig Brain: A Study Using Subcellular Fractionation and Electron Microscopic Immunocytochemistry

1 reference

12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

12 December 2020

Electronmicroscopic immunocytochemistry of pig brain shows that endopeptidase-24.11 is localized in neuronal membranes

1 reference

12 December 2020

Neutral endopeptidase modulation of septic shock.

1 reference

12 December 2020

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

1 reference

12 December 2020

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

12 December 2020

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

1 reference

12 December 2020

Cloning and characterization of adeno-associated virus type 5.

1 reference

12 December 2020

10.1523/JNEUROSCI.4792-03.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729819&resulttype=core&format=json

12 May 2020

1 reference