Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology (Q28504643)

Synaptophysin

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Glutamate receptor, metabotropic 3

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Glial fibrillary acidic protein

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Glutamate receptor, metabotropic 2

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Microtubule-associated protein tau

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Tyrosine hydroxylase

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Glutamate decarboxylase 1

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Synaptic vesicle glycoprotein 2 a

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Amyloid beta (A4) precursor protein

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Membrane metallo endopeptidase

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Microtubule-associated protein 2

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Peter Henry St George-Hyslop

author

10

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David Westaway

9

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author name string

Shinjiro Fukami

1

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24 January 2017

Kaori Watanabe

2

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24 January 2017

Nobuhisa Iwata

3

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24 January 2017

Jo Haraoka

4

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24 January 2017

Bao Lu

5

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24 January 2017

Norma P. Gerard

6

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24 January 2017

Craig Gerard

7

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24 January 2017

Paul Fraser

8

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24 January 2017

Takaomi C. Saido

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

11

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24 January 2017

1 May 2002

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24 January 2017

Neuroscience Research

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24 January 2017

43

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24 January 2017

1

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24 January 2017

39–56

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24 January 2017

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Histochemical visualization of neutral endopeptidase-24.11 (enkephalinase) activity in rat brain: cellular localization and codistribution with enkephalins in the globus pallidus

1 reference

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Differential expression of synaptic vesicle protein 2 (SV2) isoforms.

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The distribution of tau in the mammalian central nervous system

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

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Abeta-induced inflammatory processes in microglia cells of APP23 transgenic mice

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Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

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Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

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Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies

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Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice.

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7 January 2021

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

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Cortical substance P-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type

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Selective loss of central cholinergic neurons in Alzheimer's disease

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

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Interneurons of the hippocampus

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GABAergic axon terminals at perisomatic and dendritic inhibitory sites show different immunoreactivities against two GAD isoforms, GAD67 and GAD65, in the mouse hippocampus: a digitized quantitative analysis

1 reference

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Effects of intrahippocampal colchicine administration on the levels and localization of microtubule-associated proteins, tau and MAP2.

1 reference

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Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons.

1 reference

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7 January 2021

Amyloid, the presenilins and Alzheimer's disease

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain

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Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization histochemistry and immunohistochemistry.

1 reference

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Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

1 reference

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Metabolic regulation of brain Abeta by neprilysin.

1 reference

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Comparable amyloid beta-protein (A beta) 42(43) and A beta 40 deposition in the aged monkey brain.

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Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs

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Neutral endopeptidase modulation of septic shock.

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GABAergic deafferentation hypothesis of brain aging and Alzheimer's disease revisited

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

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Accumulation of murine amyloidbeta42 in a gene-dosage-dependent manner in PS1 'knock-in' mice.

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Detailed immunoautoradiographic mapping of enkephalinase (EC 3.4.24.11) in rat central nervous system: comparison with enkephalins and substance P.

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Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

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Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

1 reference

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Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain

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1 reference

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1 reference

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4013530

4013530

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference