Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells (Q40537107)

21 September 2017

Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells (English)

1 reference

21 September 2017

1 reference

Tushar B Deb

1

1 reference

21 September 2017

Christine M Coticchia

series ordinal

2

1 reference

21 September 2017

Robert B Dickson

series ordinal

3

1 reference

21 September 2017

language of work or name

English

0 references

publication date

9 July 2004

1 reference

Journal of Biological Chemistry

21 September 2017

1 reference

21 September 2017

279

1 reference

21 September 2017

38903-38911

1 reference

21 September 2017

37

1 reference

21 September 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Neuronal survival induced by neurotrophins requires calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin activates phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Suppression of EGF-induced cell proliferation by the blockade of Ca2+ mobilization and capacitative Ca2+ entry in mouse mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Overexpression of c-Myc alters G(1)/S arrest following ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Stromal influences on transformation of human mammary epithelial cells overexpressing c-myc and SV40T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calcium signaling by HBx protein in hepatitis B virus DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin protects cells from death under normal growth conditions and mitogenic starvation but plays a mediating role in cell death upon B-cell receptor stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

A single amino acid difference between alpha and beta Ca2+/calmodulin-dependent protein kinase kinase dictates sensitivity to the specific inhibitor, STO-609.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The Ca-calmodulin-dependent protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

A selective Ca2+/calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The functional consequences of mis-sense mutations affecting an intra-molecular salt bridge in arylsulphatase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Interactions between the juxtamembrane domain of the EGFR and calmodulin measured by surface plasmon resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Growth factor signaling induces metastasis genes in transformed cells: molecular connection between Akt kinase and osteopontin in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin-specific monoclonal antibodies inhibit DNA replication in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Ca2+-calmodulin promotes survival of pheromone-induced growth arrest by activation of calcineurin and Ca2+-calmodulin-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Initiating oncogenic event determines gene-expression patterns of human breast cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Regulation of mouse mammary gland development and tumorigenesis by the ERBB signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

ErbBs in mammary development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

Calmodulin signaling via the IQ motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405314200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405314200

1 reference

21 September 2017

1 reference