Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. (Q34250223)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9321394%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9321394%20AND%20SRC:MED&resulttype=core&format=json

Pawel Krzysztof Wlodarski

6 November 2019

author

8

1 reference

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6 November 2019

Tung O. Chan

10

1 reference

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6 November 2019

author name string

T Skorski

1

1 reference

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6 November 2019

A Bellacosa

2

1 reference

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6 November 2019

M Nieborowska-Skorska

3

1 reference

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6 November 2019

M Majewski

4

1 reference

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6 November 2019

R Martinez

5

1 reference

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6 November 2019

J K Choi

6

1 reference

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6 November 2019

R Trotta

7

1 reference

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6 November 2019

D Perrotti

9

1 reference

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6 November 2019

M A Wasik

11

1 reference

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6 November 2019

P N Tsichlis

12

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6 November 2019

B Calabretta

13

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6 November 2019

publication date

1 October 1997

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6 November 2019

language of work or name

0 references

1 reference

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6 November 2019

volume

16

1 reference

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6 November 2019

issue

20

1 reference

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6 November 2019

page(s)

6151-6161

1 reference

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

6 November 2019

cites work

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

6 July 2018

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

6 July 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

6 July 2018

1 reference

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

6 July 2018

1 reference

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Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase.

6 July 2018

1 reference

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PI 3-kinase activation in BCR/abl-transformed hematopoietic cells does not require interaction of p85 SH2 domains with p210 BCR/abl

6 July 2018

1 reference

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The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.

6 July 2018

1 reference

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The BCR-ABL oncogene requires both kinase activity and src-homology 2 domain to induce cytokine secretion

6 July 2018

1 reference

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SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence

6 July 2018

1 reference

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Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line

6 July 2018

1 reference

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

6 July 2018

1 reference

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Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

6 July 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

6 July 2018

1 reference

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Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase.

6 July 2018

1 reference

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Tyrosine kinase(s) regulate apoptosis and bcl-2 expression in a growth factor-dependent cell line.

6 July 2018

1 reference

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Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth

6 July 2018

1 reference

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Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase

6 July 2018

1 reference

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Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia

6 July 2018

1 reference

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Differential complementation of Bcr-Abl point mutants with c-Myc

6 July 2018

1 reference

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A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase

6 July 2018

1 reference

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Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326299

Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism.

6 July 2018

1 reference

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Phosphatidylinositol 3-kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326299

Phosphatidylinositol-3-OH kinase as a direct target of Ras

6 July 2018

1 reference

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326299

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

6 July 2018

1 reference

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Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family

6 July 2018

1 reference

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The SH2 domain of ABL is not required for factor-independent growth induced by BCR-ABL in a murine myeloid cell line.

6 July 2018

1 reference

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Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells

6 July 2018

1 reference

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Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.

6 July 2018

1 reference

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

6 July 2018

1 reference

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Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

6 July 2018

1 reference

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Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

6 July 2018

1 reference

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The v-Src SH3 Domain Binds Phosphatidylinositol 3'-Kinase

6 July 2018

1 reference

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SH2 domains recognize specific phosphopeptide sequences

6 July 2018

1 reference

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Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells

6 July 2018

1 reference

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Signaling by ABL oncogenes through cyclin D1.

6 July 2018

1 reference

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Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis

6 July 2018

1 reference

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Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

6 July 2018

1 reference

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Association of phosphatidylinositol 3-kinase with SHC in chronic myelogeneous leukemia cells.

6 July 2018

1 reference

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Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway

6 July 2018

1 reference

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Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

6 July 2018

1 reference

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Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

6 July 2018

1 reference

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Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

6 July 2018

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

6 July 2018

1 reference

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

6 July 2018

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

6 July 2018

1 reference

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Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

6 July 2018

1 reference

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BCR-ABL and BCR proteins: biochemical characterization and localization

6 July 2018

1 reference

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Molecular genetic advances in chronic myelogenous leukemia

6 July 2018

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

6 July 2018

1 reference

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Two types of phosphatidylinositol 3-kinase from bovine thymus. Monomer and heterodimer form

6 July 2018

1 reference

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Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants

6 July 2018

1 reference

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BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

6 July 2018

1 reference

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Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV

6 July 2018

1 reference

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BCR/ABL confers growth factor independence upon a murine myeloid cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326299

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

6 July 2018

1 reference

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Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

6 July 2018

1 reference

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Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology

6 July 2018

1 reference

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c-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chroni

6 July 2018

1 reference

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BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death.

28 October 2018

1 reference

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The SH2 domain of P210BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells

28 October 2018

1 reference

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28 October 2018

1 reference

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Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9321394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9321394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/16.20.6151

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9321394%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9321394%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

9321394

1 reference