ERK, PKC and PI3K/Akt pathways mediate extracellular ATP and adenosine-induced proliferation of U138-MG human glioma cell line. (Q40457686)

20 September 2017

ERK, PKC and PI3K/Akt pathways mediate extracellular ATP and adenosine-induced proliferation of U138-MG human glioma cell line. (English)

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20 September 2017

Maria C Jacques-Silva

1

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20 September 2017

Andressa Bernardi

2

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20 September 2017

Richard Rodnight

3

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20 September 2017

Guido Lenz

4

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20 September 2017

1 January 2004

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20 September 2017

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20 September 2017

67

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20 September 2017

5-6

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20 September 2017

450-459

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Environmental risk factors for primary malignant brain tumors: a review

20 September 2017

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Gliomagenesis: genetic alterations and mouse models

21 January 2018

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Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells

21 January 2018

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Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures.

21 January 2018

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Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines

21 January 2018

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Synergistic effect of acute hypoxia on flow-induced release of ATP from cultured endothelial cells

21 January 2018

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The role of protein kinase C (PKC) in the evolution and proliferation of malignant gliomas, and the application of PKC inhibition as a novel approach to anti-glioma therapy

21 January 2018

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The role of protein kinase Calpha in U-87 glioma invasion.

21 January 2018

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Tamoxifen inhibits particulate-associated protein kinase C activity, and sensitises cultured human glioblastoma cells not to etoposide but to gamma-radiation and BCNU.

21 January 2018

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Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?

21 January 2018

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PI3-kinase inhibition: a target for drug development?

21 January 2018

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The Akt/protein kinase B-dependent anti-apoptotic pathway and the mitogen-activated protein kinase cascade are alternatively activated in human glioblastoma multiforme

21 January 2018

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P2X7 receptors stimulate AKT phosphorylation in astrocytes

21 January 2018

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P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes

21 January 2018

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Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells.

21 January 2018

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AKT plays a central role in tumorigenesis

21 January 2018

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Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo

21 January 2018

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Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cells

21 January 2018

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21 January 2018

The renaissance of GSK3

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PTEN: life as a tumor suppressor

21 January 2018

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

Regulation of translation initiation by FRAP/mTOR

21 January 2018

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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Altered extracellular ATP, ADP and AMP catabolism in glioma cell lines

21 January 2018

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Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist

21 January 2018

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Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase beta

21 January 2018

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Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosis

21 January 2018

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Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

21 January 2018

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ATP-stimulated Ca2+ influx and phospholipase D activities of a rat brain-derived type-2 astrocyte cell line, RBA-2, are mediated through P2X7 receptors

21 January 2018

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Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3'-kinase-mediates PKC delta phosphorylation: role of PKC in angiogenesis

21 January 2018

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AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling

21 January 2018

1 reference

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway

21 January 2018

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Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alpha

21 January 2018

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Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.

21 January 2018

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

21 January 2018

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Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

21 January 2018

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Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

21 January 2018

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Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

21 January 2018

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Autocrine signaling through Ras regulates cell survival activity in human glioma cells: potential cross-talk between Ras and the phosphatidylinositol 3-kinase-Akt pathway

21 January 2018

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Activation of P2Y2 receptor induces c-FOS protein through a pathway involving mitogen-activated protein kinases and phosphoinositide 3-kinases in HeLa cells.

21 January 2018

1 reference

Growth-factor-dependent mitogenesis requires two distinct phases of signalling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000082930

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20 September 2017

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