AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling (Q44411064)

2 December 2017

AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling (English)

1 reference

2 December 2017

AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling (English)

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

proto-oncogene protein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706837

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

5

Gottfried Baier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706837

26 December 2023

author name string

Birgit Bauer

1

1 reference

2 December 2017

Marcel Jenny

2

1 reference

2 December 2017

Fiedrich Fresser

3

1 reference

2 December 2017

Florian Uberall

4

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

2 December 2017

24 April 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12706837

full work available at URL

26 December 2023

https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0014-5793%2803%2900287-4

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706837

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2FS0014-5793%2803%2900287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2FS0014-5793(03)00287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/S0014-5793%2803%2900287-4

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

26 December 2023

1 reference

2 December 2017

541

1 reference

2 December 2017

1-3

1 reference

2 December 2017

155-162

1 reference

Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration

2 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

T cell expressed PKCtheta demonstrates cell-type selective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Selective modulation of protein kinase C-theta during T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Protein kinase B (Akt) regulation and function in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Imaging antigen-induced PI3K activation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Fc gamma RIIB1/SHIP-mediated inhibitory signaling in B cells involves lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Lipid rafts and T cell receptor signaling: a critical re-evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Immunology. The immunological synapse--a multitasking system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

The immunological synapse: required for T cell receptor signalling or directing T cell effector function?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Transient translocation of the B cell receptor and Src homology 2 domain-containing inositol phosphatase to lipid rafts: evidence toward a role in calcium regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

Signal transduction pathways that contribute to increased protein synthesis during T-cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900287-4

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

7 January 2021

3

1 reference

https://api.crossref.org/works/10.1016/S0014-5793(03)00287-4

Science's STKE : signal transduction knowledge environment

26 December 2023

12

122

RE2

Sedwick C.E.

2002

1 reference

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Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

26 December 2023

32

1 reference

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26 December 2023

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1 reference

release_kaevakyyvfaqjeif4aumdzx2i4

2 December 2017

1 reference

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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