RNA-virus proteases counteracting host innate immunity (Q40066626)

17 September 2017

RNA-virus proteases counteracting host innate immunity (English)

1 reference

17 September 2017

2

Rolf Hilgenfeld

1 reference

17 September 2017

Jian Lei

1

1 reference

PubMed ID

28850669

17 September 2017

language of work or name

English

0 references

publication date

29 August 2017

1 reference

17 September 2017

1 reference

Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2017).

17 September 2017

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Picornavirus morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Picornavirus non-structural proteins as targets for new anti-virals with broad activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The structures of picornaviral proteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Supramolecular Architecture of the Coronavirus Particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Accessory proteins of SARS-CoV and other coronaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

A second hepatitis C virus-encoded proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Temporal modulation of an autoprotease is crucial for replication and pathogenicity of an RNA virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structure of the foot-and-mouth disease virus leader protease: a papain-like fold adapted for self-processing and eIF4G recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Production of type I interferons: plasmacytoid dendritic cells and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Regulation of type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Innate immunity to virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The inflammasome NLRs in immunity, inflammation, and associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The structural biology of Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TAB3, a new binding partner of the protein kinase TAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TAK1-dependent signaling requires functional interaction with TAB2/TAB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Toll-like receptor and RIG-I-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

MDA5 plays a critical role in interferon response during hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The NLR gene family: a standard nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Proteinase 3C of hepatitis A virus (HAV) cleaves the HAV polyprotein P2-P3 at all sites including VP1/2A and 2A/2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Intrinsic signals for the assembly of hepatitis A virus particles. Role of structural proteins VP4 and 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 2Apro targets MDA5 and MAVS in infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

MDA-5 is cleaved in poliovirus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 71 disrupts interferon signaling by reducing the level of interferon receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 71 inhibits cellular type I interferon signaling by downregulating JAK1 protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cleavage of eukaryotic translation initiation factor 4G by exogenously added hybrid proteins containing poliovirus 2Apro in HeLa cells: effects on gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cleavage site analysis in picornaviral polyproteins: discovering cellular targets by neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The viral RNA recognition sensor RIG-I is degraded during encephalomyocarditis virus (EMCV) infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Disruption of MDA5-Mediated Innate Immune Responses by the 3C Proteins of Coxsackievirus A16, Coxsackievirus A6, and Enterovirus D68.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 68 3C protease cleaves TRIF to attenuate antiviral responses mediated by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Hepatitis A virus 3C protease cleaves NEMO to impair induction of beta interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

3C Protease of Enterovirus D68 Inhibits Cellular Defense Mediated by Interferon Regulatory Factor 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cleavage of poly(A)-binding protein by poliovirus 3C protease inhibits host cell translation: a novel mechanism for host translation shutoff

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Poly(A) binding protein, C-terminally truncated by the hepatitis A virus proteinase 3C, inhibits viral translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Two initiation sites for foot-and-mouth disease virus polyprotein in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Degradation of nuclear factor kappa B during foot-and-mouth disease virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced type I interferon transcription by decreasing interferon regulatory factor 3/7 in protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Interaction between FMDV Lpro and transcription factor ADNP is required for optimal viral replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Transcriptional role of p53 in interferon-mediated antiviral immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

p53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Limited suppression of the interferon-beta production by hepatitis C virus serine protease in cultured human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF-κB signaling of IFNB1 antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

DENV inhibits type I IFN production in infected cells by cleaving human STING

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Dengue virus targets the adaptor protein MITA to subvert host innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Endoplasmic Reticulum Protein SCAP Inhibits Dengue Virus NS2B3 Protease by Suppressing Its K27-Linked Polyubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Classical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

The Npro product of classical swine fever virus interacts with IkappaBalpha, the NF-kappaB inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Recent developments in antiviral agents against enterovirus 71 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

SARS and MERS: recent insights into emerging coronaviruses

21 January 2018

1 reference

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Enterovirus 71 2C Protein Inhibits NF-κB Activation by Binding to RelA(p65)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and beta interferon secretion during viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Effects of mutation in hepatitis C virus nonstructural protein 5A on interferon resistance mediated by inhibition of PKR kinase activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12827

In vitro RNA binding of the hepatitis A virus proteinase 3C (HAV 3Cpro) to secondary structure elements within the 5' terminus of the HAV genome.

21 January 2018

1 reference

12 December 2020

Blocking human enterovirus 71 replication by targeting viral 2A protease

1 reference

12 December 2020

Serine protease of pestiviruses: determination of cleavage sites

1 reference

12 December 2020

Extremely efficient cleavage of eIF4G by picornaviral proteinases L and 2A in vitro

1 reference

12 December 2020

N-terminal protease of pestiviruses: identification of putative catalytic residues by site-directed mutagenesis

1 reference

12 December 2020

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

1 reference

12 December 2020

PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production

1 reference

12 December 2020

Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase

1 reference

12 December 2020

STAT2 and IRF9: Beyond ISGF3.

1 reference

12 December 2020

Cleavage of Poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff?

1 reference

12 December 2020

Identifiers

DOI

10.1002/1873-3468.12827

1 reference

release_cct4vq5qxjf6xnppwtzo34kvn4

17 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cct4vq5qxjf6xnppwtzo34kvn4

24 November 2022

mapped directly with Wikidata item

PubMed ID

28850669

1 reference

PubMed ID

28850669