Therapeutic Potentials of Noncoding RNAs: Targeted Delivery of ncRNAs in Cancer Cells (Q38885511)

7 September 2017

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title

Therapeutic Potentials of Noncoding RNAs: Targeted Delivery of ncRNAs in Cancer Cells (English)

1 reference

7 September 2017

Yang Liu

1

1 reference

PubMed ID

27376745

7 September 2017

Jun Wang

series ordinal

2

1 reference

PubMed ID

27376745

7 September 2017

language of work or name

English

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publication date

1 January 2016

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Advances in Experimental Medicine and Biology

7 September 2017

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7 September 2017

927

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7 September 2017

429-458

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Long noncoding RNAs and the genetics of cancer.

7 September 2017

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

MicroRNAs in cancer: biomarkers, functions and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

miR-155 gene: a typical multifunctional microRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

miR-34 - a microRNA replacement therapy is headed to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Progress in microRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Post-transcriptional gene silencing by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Many commonly used siRNAs risk off-target activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

siRNAs can function as miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Overcoming the innate immune response to small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanocrystal targeting in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Designing highly active siRNAs for therapeutic applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

siRNA Selection Server: an automated siRNA oligonucleotide prediction server

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

siRNAs: their potential as therapeutic agents--Part I. Designing of siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Sequence characteristics of functional siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Chemical modification of siRNAs for in vivo use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Chemical modification of siRNAs to improve serum stability without loss of efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

An evaluation of the toxicities of 2'-fluorouridine and 2'-fluorocytidine-HCl in F344 rats and woodchucks (Marmota monax).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Preclinical and clinical development of siRNA-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Progress and problems with the use of viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nonviral vectors for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Design and development of polymers for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

siRNA conjugate delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Mutant KRAS is a druggable target for pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

State-of-the-art gene-based therapies: the road ahead

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Recent advances with liposomes as pharmaceutical carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Liposomal siRNA nanocarriers for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Toxicity of cationic lipids and cationic polymers in gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

MicroRNA delivery by cationic lipoplexes for lung cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Targeted liposomal drug delivery in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cationic solid lipid nanoparticles reconstituted from low density lipoprotein components for delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Sterically polymer-based liposomal complexes with dual-shell structure for enhancing the siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanovector delivery of siRNA for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanoparticle-based delivery system for application of siRNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Recent advances of siRNA delivery by nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cyclodextrin-based pharmaceutics: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cationic microRNA-delivering nanovectors with bifunctional peptides for efficient treatment of PANC-1 xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Promotion of embryonic cortico-cerebral neuronogenesis by miR-124.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Polymers in small-interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cationic lipid-assisted polymeric nanoparticle mediated GATA2 siRNA delivery for synthetic lethal therapy of KRAS mutant non-small-cell lung carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Control of RNA silencing and localization by endolysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Cancer targeting potential of some ligand-anchored poly(propylene imine) dendrimers: a comparison.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Nanosized polyamidoamine (PAMAM) dendrimer-induced apoptosis mediated by mitochondrial dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: effect of the degree of quaternization and cancer targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Efficient in vitro siRNA delivery and intramuscular gene silencing using PEG-modified PAMAM dendrimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Functional delivery of siRNA in mice using dendriworms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

LHRH receptor-mediated delivery of siRNA using polyelectrolyte complex micelles self-assembled from siRNA-PEG-LHRH conjugate and PEI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-981-10-1498-7_16

10.1007/978-981-10-1498-7_16

21 January 2018

Identifiers

DOI

1 reference

7 September 2017

1 reference

PubMed ID

27376745